Atomistry » Zinc » PDB 1iml-1jan » 1is8
Atomistry »
  Zinc »
    PDB 1iml-1jan »
      1is8 »

Zinc in PDB 1is8: Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn

Enzymatic activity of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn

All present enzymatic activity of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn:
3.5.4.16;

Protein crystallography data

The structure of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn, PDB code: 1is8 was solved by N.Maita, K.Okada, K.Hatakeyama, T.Hakoshima, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 15.00 / 2.70
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 123.900, 111.430, 125.910, 90.00, 97.32, 90.00
R / Rfree (%) 21.9 / 24.5

Other elements in 1is8:

The structure of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn also contains other interesting chemical elements:

Potassium (K) 10 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn (pdb code 1is8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn, PDB code: 1is8:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Zinc binding site 1 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 1 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn3102

b:53.2
occ:1.00
 ND1 A:HIS135 2.1 34.1 1.0
SG A:CYS132 2.2 35.4 1.0
SG A:CYS203 2.4 52.2 1.0
O A:HOH3107 2.8 19.4 1.0
CE1 A:HIS135 2.8 31.6 1.0
CG A:HIS135 3.3 32.8 1.0
CB A:CYS203 3.4 52.1 1.0
CB A:CYS132 3.6 36.2 1.0
CB A:HIS135 3.9 32.2 1.0
NE2 A:HIS135 4.0 31.4 1.0
N A:HIS135 4.2 34.5 1.0
CB A:HIS134 4.2 39.1 1.0
CD2 A:HIS135 4.3 31.9 1.0
O A:HOH3112 4.4 27.7 1.0
CA A:HIS135 4.7 32.6 1.0
C A:HIS134 4.8 36.9 1.0
CA A:CYS203 4.8 53.2 1.0
ND1 A:HIS134 4.8 48.7 1.0
O A:HOH3117 4.8 30.3 1.0
CA A:HIS134 4.9 36.7 1.0
CA A:CYS132 4.9 34.6 1.0
N A:HIS134 5.0 36.5 1.0

Zinc binding site 2 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 2 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn3109

b:54.6
occ:1.00
 SG B:CYS132 2.1 37.1 1.0
ND1 B:HIS135 2.1 28.3 1.0
O B:HOH3110 2.1 5.8 1.0
SG B:CYS203 2.3 45.4 1.0
CE1 B:HIS135 2.9 29.2 1.0
CG B:HIS135 3.2 30.4 1.0
CB B:CYS203 3.2 50.4 1.0
CB B:CYS132 3.5 34.1 1.0
CB B:HIS135 3.7 31.1 1.0
NE2 B:HIS135 4.0 29.1 1.0
N B:HIS135 4.1 34.1 1.0
O B:HOH3111 4.1 11.8 1.0
CD2 B:HIS135 4.2 29.0 1.0
CB B:HIS134 4.3 40.4 1.0
CA B:HIS135 4.5 32.4 1.0
CA B:CYS203 4.7 51.6 1.0
C B:HIS134 4.7 36.4 1.0
CA B:CYS132 4.8 32.8 1.0
CA B:HIS134 4.9 37.6 1.0
ND1 B:HIS134 4.9 47.8 1.0
N B:HIS134 4.9 37.0 1.0

Zinc binding site 3 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 3 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn3107

b:55.1
occ:1.00
 ND1 C:HIS135 2.2 35.8 1.0
SG C:CYS132 2.3 40.4 1.0
O C:HOH3108 2.3 13.5 1.0
SG C:CYS203 2.4 50.4 1.0
CE1 C:HIS135 3.0 38.5 1.0
CB C:CYS203 3.1 52.4 1.0
CG C:HIS135 3.2 34.2 1.0
CB C:CYS132 3.4 34.4 1.0
CB C:HIS135 3.6 34.1 1.0
N C:HIS135 4.0 34.7 1.0
NE2 C:HIS135 4.1 38.8 1.0
CD2 C:HIS135 4.2 36.8 1.0
CB C:HIS134 4.3 39.7 1.0
CA C:HIS135 4.4 34.4 1.0
CA C:CYS203 4.6 53.6 1.0
C C:HIS134 4.7 37.9 1.0
CA C:CYS132 4.8 33.2 1.0
O D:HOH3110 4.9 26.2 1.0
CA C:HIS134 4.9 38.5 1.0
N C:HIS134 5.0 38.4 1.0

Zinc binding site 4 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 4 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn3108

b:73.0
occ:1.00
 ND1 D:HIS135 2.1 29.8 1.0
SG D:CYS132 2.2 40.6 1.0
SG D:CYS203 2.5 51.6 1.0
O D:HOH3109 2.8 38.8 1.0
CE1 D:HIS135 2.8 30.5 1.0
CG D:HIS135 3.2 29.5 1.0
CB D:CYS203 3.3 54.3 1.0
CB D:CYS132 3.6 36.5 1.0
CB D:HIS135 3.8 31.9 1.0
N D:HIS135 4.0 34.8 1.0
NE2 D:HIS135 4.0 31.9 1.0
CB D:HIS134 4.2 39.3 1.0
CD2 D:HIS135 4.2 30.2 1.0
CA D:HIS135 4.5 33.3 1.0
O D:HOH3115 4.6 48.0 1.0
C D:HIS134 4.7 36.6 1.0
CA D:CYS203 4.8 56.3 1.0
CA D:HIS134 4.8 37.0 1.0
ND1 D:HIS134 4.8 44.6 1.0
CA D:CYS132 4.9 37.0 1.0
N D:HIS134 4.9 36.7 1.0
CG D:HIS134 5.0 42.6 1.0

Zinc binding site 5 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 5 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn3105

b:57.8
occ:1.00
 O E:HOH3107 2.2 17.6 1.0
ND1 E:HIS135 2.2 34.1 1.0
SG E:CYS132 2.2 40.2 1.0
SG E:CYS203 2.3 50.2 1.0
CE1 E:HIS135 3.0 35.0 1.0
CB E:CYS203 3.1 52.8 1.0
CG E:HIS135 3.2 33.2 1.0
CB E:CYS132 3.5 36.0 1.0
CB E:HIS135 3.7 32.6 1.0
N E:HIS135 4.1 36.0 1.0
NE2 E:HIS135 4.1 35.0 1.0
CD2 E:HIS135 4.2 33.3 1.0
CB E:HIS134 4.4 41.1 1.0
O E:HOH3110 4.5 33.6 1.0
CA E:HIS135 4.5 34.5 1.0
CA E:CYS203 4.5 54.1 1.0
O A:HOH3109 4.6 33.3 1.0
C E:HIS134 4.8 38.5 1.0
CA E:CYS132 4.9 36.8 1.0
C E:CYS203 5.0 57.6 1.0

Zinc binding site 6 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 6 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn3110

b:62.3
occ:1.00
 SG F:CYS132 2.2 44.5 1.0
ND1 F:HIS135 2.2 37.4 1.0
O F:HOH3111 2.4 18.3 1.0
SG F:CYS203 2.4 52.7 1.0
CE1 F:HIS135 2.9 38.2 1.0
CB F:CYS203 3.2 53.8 1.0
CG F:HIS135 3.4 35.7 1.0
CB F:CYS132 3.5 37.8 1.0
CB F:HIS135 3.9 34.4 1.0
NE2 F:HIS135 4.1 37.9 1.0
N F:HIS135 4.1 37.0 1.0
CB F:HIS134 4.3 41.4 1.0
CD2 F:HIS135 4.3 36.8 1.0
CA F:HIS135 4.6 35.5 1.0
CA F:CYS203 4.7 54.9 1.0
O F:HOH3120 4.8 28.0 1.0
CA F:CYS132 4.8 36.7 1.0
C F:HIS134 4.8 39.8 1.0
ND1 F:HIS134 4.9 49.4 1.0
CA F:HIS134 4.9 39.3 1.0

Zinc binding site 7 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 7 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Zn3103

b:56.2
occ:1.00
 ND1 G:HIS135 2.2 36.0 1.0
SG G:CYS132 2.2 40.1 1.0
O G:HOH3104 2.3 16.1 1.0
SG G:CYS203 2.4 51.4 1.0
CE1 G:HIS135 2.9 36.8 1.0
CG G:HIS135 3.2 35.2 1.0
CB G:CYS203 3.2 52.6 1.0
CB G:CYS132 3.4 36.4 1.0
CB G:HIS135 3.7 35.0 1.0
N G:HIS135 4.0 37.1 1.0
NE2 G:HIS135 4.1 36.0 1.0
CB G:HIS134 4.2 42.1 1.0
CD2 G:HIS135 4.2 35.5 1.0
O G:HOH3111 4.4 35.5 1.0
CA G:HIS135 4.5 35.4 1.0
O G:HOH3106 4.6 22.4 1.0
CA G:CYS203 4.7 54.1 1.0
C G:HIS134 4.7 39.1 1.0
CA G:CYS132 4.8 35.3 1.0
CA G:HIS134 4.9 39.1 1.0
ND1 G:HIS134 4.9 49.4 1.0
N G:HIS134 4.9 38.4 1.0

Zinc binding site 8 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 8 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn3104

b:49.8
occ:1.00
 ND1 H:HIS135 2.1 31.7 1.0
SG H:CYS203 2.3 49.1 1.0
O H:HOH3105 2.3 9.9 1.0
SG H:CYS132 2.4 40.8 1.0
CE1 H:HIS135 2.9 32.1 1.0
CG H:HIS135 3.2 32.5 1.0
CB H:CYS203 3.2 51.4 1.0
CB H:CYS132 3.6 34.2 1.0
CB H:HIS135 3.7 33.5 1.0
NE2 H:HIS135 4.0 31.4 1.0
N H:HIS135 4.1 35.0 1.0
O H:HOH3120 4.1 27.5 1.0
CD2 H:HIS135 4.2 31.2 1.0
CB H:HIS134 4.3 39.8 1.0
CA H:HIS135 4.5 33.9 1.0
CA H:CYS203 4.7 53.6 1.0
C H:HIS134 4.8 37.1 1.0
CA H:CYS132 5.0 33.2 1.0
CA H:HIS134 5.0 37.8 1.0

Zinc binding site 9 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 9 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn3101

b:50.2
occ:1.00
 SG I:CYS203 1.8 43.9 1.0
SG I:CYS132 1.9 34.3 1.0
ND1 I:HIS135 2.2 32.9 1.0
CE1 I:HIS135 3.0 32.0 1.0
CB I:CYS203 3.1 51.7 1.0
CG I:HIS135 3.3 30.4 1.0
CB I:CYS132 3.4 32.1 1.0
O I:HOH3102 3.5 78.6 1.0
CB I:HIS135 3.8 29.5 1.0
NE2 I:HIS135 4.1 29.4 1.0
N I:HIS135 4.1 30.1 1.0
CD2 I:HIS135 4.3 29.6 1.0
CB I:HIS134 4.3 34.7 1.0
O I:HOH3111 4.4 21.8 1.0
CA I:CYS203 4.5 52.5 1.0
CA I:HIS135 4.6 29.8 1.0
O J:HOH3112 4.7 29.2 1.0
CA I:CYS132 4.8 32.7 1.0
C I:HIS134 4.9 34.0 1.0
C I:CYS203 5.0 56.0 1.0
CA I:HIS134 5.0 33.3 1.0

Zinc binding site 10 out of 10 in 1is8

Go back to Zinc Binding Sites List in 1is8
Zinc binding site 10 out of 10 in the Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 10 of Crystal Structure of Rat Gtpchi/Gfrp Stimulatory Complex Plus Zn within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn3106

b:53.1
occ:1.00
 ND1 J:HIS135 2.2 29.2 1.0
SG J:CYS132 2.3 33.6 1.0
O J:HOH3117 2.4 16.1 1.0
SG J:CYS203 2.4 46.2 1.0
O J:HOH3107 2.7 46.3 1.0
CE1 J:HIS135 2.9 27.4 1.0
CG J:HIS135 3.4 27.9 1.0
CB J:CYS203 3.5 50.7 1.0
CB J:CYS132 3.6 34.0 1.0
CB J:HIS135 3.9 28.4 1.0
NE2 J:HIS135 4.1 29.3 1.0
N J:HIS135 4.1 31.3 1.0
CB J:HIS134 4.2 38.7 1.0
O J:HOH3116 4.2 22.9 1.0
CD2 J:HIS135 4.4 29.2 1.0
CA J:HIS135 4.7 30.7 1.0
C J:HIS134 4.8 34.7 1.0
ND1 J:HIS134 4.8 45.9 1.0
CA J:HIS134 4.9 35.7 1.0
CA J:CYS203 4.9 52.3 1.0
CA J:CYS132 4.9 33.9 1.0
CG J:HIS134 5.0 43.2 1.0
N J:HIS134 5.0 36.7 1.0

Reference:

N.Maita, K.Okada, K.Hatakeyama, T.Hakoshima. Crystal Structure of the Stimulatory Complex of Gtp Cyclohydrolase I and Its Feedback Regulatory Protein Gfrp. Proc.Natl.Acad.Sci.Usa V. 99 1212 2002.
ISSN: ISSN 0027-8424
PubMed: 11818540
DOI: 10.1073/PNAS.022646999
Page generated: Sun Oct 13 03:10:47 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy