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Atomistry » Zinc » PDB 1i96-1im5 » 1if7 » |
Zinc in PDB 1if7: Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-BenzamideEnzymatic activity of Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide
All present enzymatic activity of Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide, PDB code: 1if7
was solved by
B.A.Grzybowski,
A.V.Ishchenko,
C.-Y.Kim,
G.Topalov,
R.Chapman,
D.W.Christianson,
G.M.Whitesides,
E.I.Shakhnovich,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1if7:
The structure of Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide
(pdb code 1if7). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide, PDB code: 1if7: Zinc binding site 1 out of 1 in 1if7Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase II Complexed with (R)-N-(3-Indol-1-Yl-2-Methyl- Propyl)-4-Sulfamoyl-Benzamide
![]() Mono view ![]() Stereo pair view
Reference:
B.A.Grzybowski,
A.V.Ishchenko,
C.Y.Kim,
G.Topalov,
R.Chapman,
D.W.Christianson,
G.M.Whitesides,
E.I.Shakhnovich.
Combinatorial Computational Method Gives New Picomolar Ligands For A Known Enzyme. Proc.Natl.Acad.Sci.Usa V. 99 1270 2002.
Page generated: Wed Dec 16 02:52:43 2020
ISSN: ISSN 0027-8424 PubMed: 11818565 DOI: 10.1073/PNAS.032673399 |
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