|
Atomistry » Zinc » PDB 1hxy-1i95 » 1i8z | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1hxy-1i95 » 1i8z » |
Zinc in PDB 1i8z: Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- DioxideEnzymatic activity of Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide
All present enzymatic activity of Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide, PDB code: 1i8z
was solved by
C.-Y.Kim,
J.S.Chang,
J.Liao,
J.A.May,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1i8z:
The structure of Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide
(pdb code 1i8z). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide, PDB code: 1i8z: Zinc binding site 1 out of 1 in 1i8zGo back to Zinc Binding Sites List in 1i8z
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase II Complexed with Al-6629 2H-Thieno[3,2-E]-1,2- Thiazine-6-Sulfonamide, 2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1- Dioxide
Mono view Stereo pair view
Reference:
C.Y.Kim,
D.A.Whittington,
J.S.Chang,
J.Liao,
J.A.May,
D.W.Christianson.
Structural Aspects of Isozyme Selectivity in the Binding of Inhibitors to Carbonic Anhydrases II and IV. J.Med.Chem. V. 45 888 2002.
Page generated: Sun Oct 13 02:57:19 2024
ISSN: ISSN 0022-2623 PubMed: 11831900 DOI: 10.1021/JM010163D |
Last articlesW in 8QLNW in 8RJA V in 8WTN Te in 8QLN Re in 9GHX Rb in 8Z5C Ni in 9C0T Ni in 9C0S Ni in 9GP1 Ni in 9FYO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |