Atomistry » Zinc » PDB 1h71-1hld » 1hcq
Atomistry »
  Zinc »
    PDB 1h71-1hld »
      1hcq »

Zinc in PDB 1hcq: The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements

Protein crystallography data

The structure of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements, PDB code: 1hcq was solved by J.W.R.Schwabe, L.Chapman, J.T.Finch, D.Rhodes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.40
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.600, 90.800, 114.600, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Zinc Binding Sites:

The binding sites of Zinc atom in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements (pdb code 1hcq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements, PDB code: 1hcq:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 1 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn598

b:24.0
occ:1.00
 SG A:CYS27 2.1 19.2 1.0
SG A:CYS24 2.2 24.9 1.0
SG A:CYS10 2.2 23.7 1.0
SG A:CYS7 2.5 22.5 1.0
CB A:CYS7 3.2 18.6 1.0
CB A:CYS10 3.3 22.2 1.0
CB A:CYS27 3.3 19.4 1.0
CB A:CYS24 3.4 22.8 1.0
N A:CYS10 3.7 23.9 1.0
N A:CYS27 3.9 17.9 1.0
N A:CYS24 4.1 20.9 1.0
CA A:CYS10 4.1 23.5 1.0
CA A:CYS27 4.2 16.8 1.0
CA A:CYS24 4.3 19.4 1.0
NH1 A:ARG56 4.4 23.4 1.0
CB A:VAL9 4.5 25.4 1.0
C A:VAL9 4.7 25.0 1.0
CA A:CYS7 4.7 19.7 1.0
C A:CYS10 4.7 25.3 1.0
N A:ASP12 4.8 27.8 1.0
CB A:ASP12 4.8 26.0 1.0
N A:ASN11 4.8 25.7 1.0
CD A:ARG56 4.8 22.0 1.0
NH2 A:ARG63 4.9 20.2 1.0
CA A:VAL9 4.9 25.8 1.0
C A:CYS24 5.0 16.6 1.0
O A:CYS24 5.0 16.6 1.0
N A:VAL9 5.0 28.2 1.0
C A:GLY26 5.0 19.0 1.0

Zinc binding site 2 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 2 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn599

b:21.2
occ:1.00
 SG A:CYS49 2.1 19.4 1.0
SG A:CYS59 2.2 21.1 1.0
SG A:CYS43 2.2 20.4 1.0
SG A:CYS62 2.4 23.3 1.0
CB A:CYS59 3.2 18.6 1.0
CB A:CYS49 3.3 21.6 1.0
CB A:CYS62 3.4 22.1 1.0
CB A:CYS43 3.4 22.2 1.0
CD A:PRO44 3.8 16.0 1.0
CA A:CYS43 4.0 24.0 1.0
N A:CYS49 4.1 26.1 1.0
N A:CYS62 4.2 21.5 1.0
CA A:CYS49 4.3 23.9 1.0
CA A:ASN47 4.3 24.8 1.0
O A:HOH608 4.3 24.0 1.0
CA A:CYS62 4.3 23.2 1.0
N A:ASN47 4.4 25.7 1.0
N A:PRO44 4.5 15.6 1.0
CA A:CYS59 4.6 20.6 1.0
N A:GLN48 4.7 22.3 1.0
C A:CYS43 4.7 19.4 1.0
C A:ASN47 4.8 24.5 1.0
CG A:PRO44 4.8 15.1 1.0
N A:ALA45 4.9 19.6 1.0
CB A:ALA61 5.0 21.4 1.0

Zinc binding site 3 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 3 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn598

b:25.2
occ:1.00
 SG B:CYS24 2.1 28.7 1.0
SG B:CYS27 2.1 18.2 1.0
SG B:CYS10 2.2 24.5 1.0
SG B:CYS7 2.3 31.2 1.0
CB B:CYS7 3.2 31.9 1.0
CB B:CYS10 3.3 26.1 1.0
CB B:CYS24 3.3 26.9 1.0
CB B:CYS27 3.4 16.1 1.0
NH1 B:ARG56 3.6 30.3 1.0
N B:CYS10 3.6 27.7 1.0
N B:CYS27 3.9 12.2 1.0
N B:CYS24 4.0 28.6 1.0
CA B:CYS10 4.0 26.2 1.0
CA B:CYS27 4.3 11.5 1.0
CA B:CYS24 4.3 25.5 1.0
CB B:VAL9 4.3 27.8 1.0
N B:ASN11 4.6 29.5 1.0
C B:VAL9 4.6 28.7 1.0
C B:CYS10 4.7 28.6 1.0
CA B:CYS7 4.7 31.4 1.0
NH2 B:ARG63 4.7 20.9 1.0
CB B:ASP12 4.7 31.2 1.0
CZ B:ARG56 4.7 28.6 1.0
N B:ASP12 4.7 31.3 1.0
CD B:ARG56 4.8 27.1 1.0
CA B:VAL9 4.9 29.0 1.0
CG1 B:VAL9 4.9 30.8 1.0
C B:CYS24 4.9 22.1 1.0
N B:VAL9 5.0 34.1 1.0

Zinc binding site 4 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 4 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn599

b:23.4
occ:1.00
 SG B:CYS49 2.1 20.8 1.0
SG B:CYS59 2.2 18.8 1.0
SG B:CYS43 2.2 21.4 1.0
SG B:CYS62 2.4 23.8 1.0
CB B:CYS59 3.1 19.1 1.0
CB B:CYS49 3.3 22.2 1.0
CB B:CYS62 3.3 20.8 1.0
CB B:CYS43 3.5 18.4 1.0
N B:CYS49 3.8 24.5 1.0
CA B:CYS43 4.0 23.0 1.0
N B:CYS62 4.1 16.9 1.0
CA B:CYS49 4.1 23.4 1.0
CD B:PRO44 4.1 21.6 1.0
CA B:CYS62 4.3 20.6 1.0
O B:HOH615 4.3 22.1 1.0
CA B:ASN47 4.4 32.8 1.0
N B:GLN48 4.5 26.9 1.0
CA B:CYS59 4.5 22.2 1.0
N B:ASN47 4.5 35.2 1.0
N B:PRO44 4.7 22.2 1.0
C B:CYS43 4.8 23.8 1.0
CG B:PRO44 4.8 23.5 1.0
C B:ASN47 4.8 30.8 1.0
C B:GLN48 4.9 24.3 1.0

Zinc binding site 5 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 5 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn598

b:26.8
occ:1.00
 SG E:CYS27 2.0 24.3 1.0
SG E:CYS10 2.1 26.3 1.0
SG E:CYS24 2.2 28.2 1.0
SG E:CYS7 2.4 29.0 1.0
CB E:CYS7 3.1 24.0 1.0
CB E:CYS10 3.1 27.4 1.0
N E:CYS10 3.6 29.9 1.0
CB E:CYS27 3.6 25.0 1.0
CB E:CYS24 3.6 27.0 1.0
CA E:CYS10 3.9 29.3 1.0
N E:CYS24 4.0 26.0 1.0
N E:CYS27 4.0 24.3 1.0
CA E:CYS24 4.3 23.3 1.0
CA E:CYS27 4.4 23.4 1.0
CB E:VAL9 4.4 28.6 1.0
NH2 E:ARG63 4.5 33.8 1.0
C E:VAL9 4.5 28.3 1.0
C E:CYS10 4.6 33.6 1.0
CA E:CYS7 4.6 25.4 1.0
CA E:VAL9 4.8 28.9 1.0
N E:VAL9 4.8 31.9 1.0
CB E:ASP12 4.8 33.8 1.0
N E:ASN11 4.9 34.3 1.0
CG1 E:VAL9 4.9 29.0 1.0
N E:ASP12 5.0 31.6 1.0
C E:CYS24 5.0 22.1 1.0

Zinc binding site 6 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 6 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn599

b:39.5
occ:1.00
 SG E:CYS49 2.0 39.1 1.0
SG E:CYS62 2.3 42.5 1.0
SG E:CYS43 2.4 43.1 1.0
SG E:CYS59 2.4 33.7 1.0
CB E:CYS59 3.2 29.1 1.0
CB E:CYS62 3.3 39.0 1.0
CB E:CYS49 3.4 38.7 1.0
CB E:CYS43 3.5 44.2 1.0
N E:CYS49 3.8 37.8 1.0
O E:HOH609 4.1 38.7 1.0
CA E:CYS49 4.1 36.4 1.0
N E:CYS62 4.2 36.5 1.0
O E:HOH611 4.2 50.5 1.0
CA E:CYS62 4.3 38.6 1.0
CA E:CYS43 4.4 42.3 1.0
CD E:PRO44 4.4 41.9 1.0
CA E:ASN47 4.5 41.7 1.0
N E:GLN48 4.5 41.0 1.0
N E:ASN47 4.5 43.3 1.0
CB E:ALA61 4.6 38.5 1.0
CA E:CYS59 4.6 29.2 1.0
C E:ASN47 4.8 40.1 1.0
C E:GLN48 4.9 39.2 1.0
O E:CYS59 5.0 35.5 1.0

Zinc binding site 7 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 7 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn598

b:32.0
occ:1.00
 SG F:CYS27 2.1 26.1 1.0
SG F:CYS10 2.2 29.9 1.0
SG F:CYS24 2.3 33.4 1.0
SG F:CYS7 2.4 33.8 1.0
CB F:CYS10 3.0 26.0 1.0
N F:CYS10 3.3 30.2 1.0
CB F:CYS7 3.3 27.5 1.0
CB F:CYS24 3.5 28.2 1.0
CB F:CYS27 3.5 23.1 1.0
CA F:CYS10 3.7 26.3 1.0
N F:CYS27 3.9 23.8 1.0
N F:CYS24 4.1 31.3 1.0
O F:HOH600 4.1 39.3 1.0
CA F:CYS27 4.3 21.3 1.0
CA F:CYS24 4.3 25.6 1.0
CB F:VAL9 4.3 37.3 1.0
C F:VAL9 4.3 32.8 1.0
C F:CYS10 4.5 29.3 1.0
CA F:CYS7 4.7 26.6 1.0
CA F:VAL9 4.7 35.2 1.0
N F:ASN11 4.8 32.9 1.0
N F:VAL9 4.8 37.5 1.0
CG1 F:VAL9 4.9 39.5 1.0
C F:CYS24 4.9 21.4 1.0

Zinc binding site 8 out of 8 in 1hcq

Go back to Zinc Binding Sites List in 1hcq
Zinc binding site 8 out of 8 in the The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn599

b:39.2
occ:1.00
 SG F:CYS49 2.1 31.6 1.0
SG F:CYS43 2.3 35.2 1.0
SG F:CYS59 2.4 33.1 1.0
SG F:CYS62 2.5 40.7 1.0
CB F:CYS59 3.1 33.0 1.0
CB F:CYS49 3.1 34.8 1.0
CB F:CYS62 3.5 37.4 1.0
CB F:CYS43 3.5 35.7 1.0
N F:CYS49 3.7 36.2 1.0
CD F:PRO44 3.7 39.7 1.0
CA F:CYS49 4.0 36.4 1.0
CA F:CYS43 4.2 37.5 1.0
O F:HOH608 4.3 33.6 1.0
N F:CYS62 4.3 34.9 1.0
CA F:ASN47 4.3 39.0 1.0
N F:ASN47 4.4 39.7 1.0
CG F:PRO44 4.5 38.9 1.0
CA F:CYS62 4.5 36.6 1.0
N F:GLN48 4.5 33.1 1.0
CA F:CYS59 4.6 33.1 1.0
O F:HOH607 4.7 45.2 1.0
N F:PRO44 4.7 38.3 1.0
C F:ASN47 4.8 37.8 1.0
C F:GLN48 4.8 33.5 1.0
C F:CYS43 4.9 38.3 1.0
O F:CYS59 4.9 38.1 1.0
CB F:ALA61 5.0 43.6 1.0

Reference:

J.W.Schwabe, L.Chapman, J.T.Finch, D.Rhodes. The Crystal Structure of the Estrogen Receptor Dna-Binding Domain Bound to Dna: How Receptors Discriminate Between Their Response Elements. Cell(Cambridge,Mass.) V. 75 567 1993.
ISSN: ISSN 0092-8674
PubMed: 8221895
DOI: 10.1016/0092-8674(93)90390-C
Page generated: Sun Oct 13 02:07:27 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy