Zinc in PDB 1ha5: Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition.

The structure of Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition., PDB code: 1ha5 was solved by M.D.Baker, D.M.Gutman, A.C.Papageorgiou, C.M.Collins, K.R.Acharya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.60 / 2.82
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	126.946, 101.320, 82.019, 90.00, 90.00, 90.00
R / Rfree (%)	21.4 / 28.3

The binding sites of Zinc atom in the Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition. (pdb code 1ha5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition., PDB code: 1ha5:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2221 b:50.8 occ:1.00 OE1 A:GLU1033 2.2 15.3 1.0 OD2 A:ASP1077 2.2 28.2 1.0 NE2 A:HIS1110 2.3 20.0 1.0 OD1 A:ASP1077 2.5 28.2 1.0 CG A:ASP1077 2.6 28.2 1.0 CD2 A:HIS1106 2.7 45.0 1.0 CD A:GLU1033 2.8 15.3 1.0 OE2 A:GLU1033 2.9 15.3 1.0 CG A:HIS1106 3.0 45.0 1.0 NE2 A:HIS1106 3.0 45.0 1.0 CD2 A:HIS1110 3.0 20.0 1.0 CE1 A:HIS1110 3.4 20.0 1.0 ND1 A:HIS1106 3.4 45.0 1.0 CE1 A:HIS1106 3.5 45.0 1.0 CB A:HIS1106 3.7 45.0 1.0 CA A:HIS1106 3.9 28.1 1.0 O A:HIS1106 4.1 28.1 1.0 CB A:ASP1077 4.1 28.2 1.0 CG A:HIS1110 4.2 20.0 1.0 CG A:GLU1033 4.2 15.3 1.0 O A:GLU1033 4.3 38.5 1.0 ND1 A:HIS1110 4.4 20.0 1.0 C A:HIS1106 4.4 28.1 1.0 C A:GLU1033 4.5 38.5 1.0 O A:HOH2019 4.6 17.1 1.0 CB A:GLU1033 4.6 15.3 1.0 CA A:GLU1033 4.6 38.5 1.0

Zinc binding site 2 out of 4 in the Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn3221 b:50.8 occ:1.00 OE1 B:GLU2033 2.0 29.3 1.0 NE2 B:HIS2110 2.2 23.9 1.0 ND1 B:HIS2106 2.3 50.2 1.0 OD2 B:ASP2077 2.4 24.7 1.0 OD1 B:ASP2077 2.5 24.7 1.0 CG B:ASP2077 2.7 24.7 1.0 CE1 B:HIS2110 3.0 23.9 1.0 CE1 B:HIS2106 3.1 50.2 1.0 CD B:GLU2033 3.2 29.3 1.0 CG B:HIS2106 3.3 50.2 1.0 CD2 B:HIS2110 3.4 23.9 1.0 CB B:HIS2106 3.7 50.2 1.0 OE2 B:GLU2033 3.8 29.3 1.0 CA B:HIS2106 3.9 23.7 1.0 O B:HIS2106 4.0 23.7 1.0 O B:GLU2033 4.0 53.5 1.0 ND1 B:HIS2110 4.2 23.9 1.0 O B:HOH3016 4.2 22.5 1.0 CB B:ASP2077 4.3 24.7 1.0 CG B:GLU2033 4.3 29.3 1.0 NE2 B:HIS2106 4.3 50.2 1.0 C B:GLU2033 4.3 53.5 1.0 CD2 B:HIS2106 4.4 50.2 1.0 CB B:GLU2033 4.4 29.3 1.0 C B:HIS2106 4.4 23.7 1.0 CA B:GLU2033 4.4 53.5 1.0 CG B:HIS2110 4.4 23.9 1.0 O B:HOH3012 4.6 37.5 1.0 N B:ASN2034 5.0 44.7 1.0

Zinc binding site 3 out of 4 in the Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition. within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn4221 b:50.8 occ:1.00 OE1 C:GLU3033 2.1 19.6 1.0 NE2 C:HIS3110 2.1 26.8 1.0 ND1 C:HIS3106 2.2 9.8 1.0 OD2 C:ASP3077 2.3 16.7 1.0 OD1 C:ASP3077 2.6 16.7 1.0 CG C:ASP3077 2.8 16.7 1.0 CE1 C:HIS3110 2.8 26.8 1.0 CE1 C:HIS3106 3.1 9.8 1.0 CD2 C:HIS3110 3.2 26.8 1.0 CG C:HIS3106 3.3 9.8 1.0 CD C:GLU3033 3.3 19.6 1.0 CB C:HIS3106 3.7 9.8 1.0 CA C:HIS3106 3.8 35.3 1.0 ND1 C:HIS3110 4.0 26.8 1.0 O C:HIS3106 4.0 35.3 1.0 OE2 C:GLU3033 4.0 19.6 1.0 CG C:HIS3110 4.2 26.8 1.0 NE2 C:HIS3106 4.2 9.8 1.0 CB C:ASP3077 4.3 16.7 1.0 C C:HIS3106 4.3 35.3 1.0 CG C:GLU3033 4.3 19.6 1.0 CD2 C:HIS3106 4.4 9.8 1.0 CB C:GLU3033 4.5 19.6 1.0 CA C:GLU3033 4.6 38.9 1.0 O C:HOH2030 4.6 32.5 1.0 C C:GLU3033 4.7 38.9 1.0 O C:GLU3033 4.9 38.9 1.0 N C:ASN3034 4.9 12.6 1.0

Zinc binding site 4 out of 4 in the Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structural Features of A Zinc-Binding Site in the Superantigen Streptococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition. within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn5221 b:50.8 occ:1.00 OD1 D:ASP4077 2.2 59.7 1.0 ND1 D:HIS4106 2.2 30.8 1.0 OE1 D:GLU4033 2.3 55.4 1.0 NE2 D:HIS4110 2.5 47.1 1.0 CG D:ASP4077 2.6 59.7 1.0 OD2 D:ASP4077 2.6 59.7 1.0 CE1 D:HIS4106 2.8 30.8 1.0 CE1 D:HIS4110 2.8 47.1 1.0 CD D:GLU4033 3.0 55.4 1.0 CG D:HIS4106 3.3 30.8 1.0 OE2 D:GLU4033 3.5 55.4 1.0 CD2 D:HIS4110 3.8 47.1 1.0 CB D:ASP4077 3.8 59.7 1.0 NE2 D:HIS4106 3.9 30.8 1.0 CB D:HIS4106 3.9 30.8 1.0 CA D:GLU4033 3.9 42.1 1.0 CB D:GLU4033 3.9 55.4 1.0 C D:GLU4033 4.0 42.1 1.0 CG D:GLU4033 4.1 55.4 1.0 O D:GLU4033 4.1 42.1 1.0 CD2 D:HIS4106 4.1 30.8 1.0 ND1 D:HIS4110 4.1 47.1 1.0 CA D:HIS4106 4.3 31.0 1.0 O D:HIS4106 4.5 31.0 1.0 N D:ASN4034 4.6 28.1 1.0 CG D:HIS4110 4.6 47.1 1.0 CA D:ASP4077 4.7 52.1 1.0 C D:HIS4106 4.9 31.0 1.0

M.D.Baker, D.M.Gutman, A.C.Papageorgiou, C.M.Collins, K.R.Acharya. Structural Features of A Zinc Binding Site in the Superantigen Strepococcal Pyrogenic Exotoxin A (SPEA1): Implications For Mhc Class II Recognition. Protein Sci. V. 10 1268 2001.
ISSN: ISSN 0961-8368
PubMed: 11369867
DOI: 10.1110/PS.330101