Zinc in PDB 1gjp: Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid

All present enzymatic activity of Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid:
4.2.1.24;

The structure of Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid, PDB code: 1gjp was solved by P.T.Erskine, L.Coates, R.Newbold, A.A.Brindley, S.P.Wood, M.J.Warren, J.B.Cooper, P.M.Shoolingin-Jordan, R.Neier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.40 / 1.80
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	103.500, 103.500, 168.200, 90.00, 90.00, 90.00
R / Rfree (%)	26.5 / 32.9

The binding sites of Zinc atom in the Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid (pdb code 1gjp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid, PDB code: 1gjp:

Zinc binding site 1 out of 1 in the Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Schiff-Base Complex of Yeast 5-Aminolaevulinic Acid Dehydratase with 4-Oxosebacic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn400 b:37.2 occ:1.00 O A:HOH2465 2.0 42.1 1.0 SG A:CYS143 2.3 42.5 1.0 SG A:CYS133 2.3 38.3 1.0 SG A:CYS135 2.3 44.1 1.0 CB A:CYS133 3.3 18.9 1.0 CB A:CYS143 3.3 57.1 1.0 CB A:CYS135 3.3 33.7 1.0 NH1 A:ARG232 3.6 27.2 1.0 O A:HOH2391 3.7 45.0 1.0 O A:HOH2359 3.9 40.1 1.0 CA A:CYS143 4.0 57.6 1.0 O A:HOH2326 4.1 33.4 1.0 OG A:SER179 4.1 36.2 1.0 N A:CYS135 4.2 24.3 1.0 C8 A:4OX363 4.3 53.9 1.0 O A:SER179 4.3 23.8 1.0 CA A:CYS135 4.4 29.7 1.0 CA A:ASP180 4.6 31.1 1.0 CA A:CYS133 4.7 21.8 1.0 C A:SER179 4.7 30.8 1.0 N A:CYS143 4.7 50.2 1.0 O A:HOH2330 4.7 34.3 1.0 CZ A:ARG232 4.8 43.3 1.0 N A:LEU134 4.8 27.7 1.0 N A:ASP180 4.8 35.1 1.0

P.T.Erskine, L.Coates, R.Newbold, A.A.Brindley, F.Stauffer, S.P.Wood, M.J.Warren, J.B.Cooper, P.M.Shoolingin-Jordan, R.Neier. The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors Febs Lett. V. 503 196 2001.
ISSN: ISSN 0014-5793
PubMed: 11513881
DOI: 10.1016/S0014-5793(01)02721-1