Atomistry » Zinc » PDB 1f6u-1fp0 » 1fbl
Atomistry »
  Zinc »
    PDB 1f6u-1fp0 »
      1fbl »

Zinc in PDB 1fbl: Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller

Enzymatic activity of Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller

All present enzymatic activity of Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller:
3.4.24.7;

Protein crystallography data

The structure of Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller, PDB code: 1fbl was solved by J.Li, P.Brick, D.M.Blow, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 9.00 / 2.50
Space group I 41
Cell size a, b, c (Å), α, β, γ (°) 161.140, 161.140, 52.220, 90.00, 90.00, 90.00
R / Rfree (%) 21.7 / n/a

Other elements in 1fbl:

The structure of Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller also contains other interesting chemical elements:

Calcium (Ca) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller (pdb code 1fbl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller, PDB code: 1fbl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 1fbl

Go back to Zinc Binding Sites List in 1fbl
Zinc binding site 1 out of 2 in the Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn997

b:31.8
occ:1.00
OD2 A:ASP170 1.9 34.0 1.0
NE2 A:HIS183 2.1 19.9 1.0
ND1 A:HIS196 2.2 21.5 1.0
NE2 A:HIS168 2.6 33.8 1.0
CD2 A:HIS168 2.9 33.7 1.0
CE1 A:HIS183 2.9 20.1 1.0
CG A:ASP170 3.0 34.2 1.0
CE1 A:HIS196 3.1 21.4 1.0
CG A:HIS196 3.2 21.4 1.0
CD2 A:HIS183 3.2 20.8 1.0
OD1 A:ASP170 3.4 34.4 1.0
CB A:HIS196 3.5 21.2 1.0
CE1 A:HIS168 3.8 33.8 1.0
CZ A:PHE185 4.0 25.5 1.0
ND1 A:HIS183 4.0 20.4 1.0
O A:SER172 4.1 32.1 1.0
NE2 A:HIS196 4.1 21.7 1.0
CG A:HIS168 4.2 33.8 1.0
CD2 A:HIS196 4.2 21.6 1.0
CG A:HIS183 4.2 20.8 1.0
CB A:ASP170 4.2 34.4 1.0
CE1 A:PHE185 4.4 25.6 1.0
ND1 A:HIS168 4.6 33.7 1.0
CE2 A:PHE174 4.8 27.1 1.0
CG2 A:VAL164 4.8 25.6 1.0
CZ A:PHE174 4.9 26.9 1.0
CA A:HIS196 5.0 21.0 1.0

Zinc binding site 2 out of 2 in 1fbl

Go back to Zinc Binding Sites List in 1fbl
Zinc binding site 2 out of 2 in the Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Full-Length Porcine Synovial Collagenase (MMP1) Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta- Propeller within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn998

b:25.6
occ:1.00
O1 A:HTA900 2.0 21.3 1.0
O2 A:HTA900 2.0 20.1 1.0
NE2 A:HIS218 2.4 16.4 1.0
NE2 A:HIS228 2.5 23.8 1.0
NE2 A:HIS222 2.6 19.4 1.0
C1 A:HTA900 2.6 19.9 1.0
N1 A:HTA900 2.7 20.6 1.0
CD2 A:HIS218 3.1 16.9 1.0
CD2 A:HIS228 3.3 23.5 1.0
CD2 A:HIS222 3.4 19.3 1.0
CE1 A:HIS218 3.5 16.7 1.0
CE1 A:HIS228 3.5 24.0 1.0
CE1 A:HIS222 3.7 19.3 1.0
C2 A:HTA900 4.2 19.0 1.0
CG A:HIS218 4.3 17.1 1.0
O A:HOH545 4.3 28.6 1.0
CG A:HIS228 4.5 23.5 1.0
ND1 A:HIS218 4.5 16.8 1.0
OE1 A:GLU219 4.5 17.8 1.0
O A:HOH505 4.5 11.4 1.0
ND1 A:HIS228 4.5 23.6 1.0
CG A:HIS222 4.6 19.5 1.0
ND1 A:HIS222 4.7 19.4 1.0
C3 A:HTA900 4.8 18.0 1.0
C5 A:HTA900 4.9 17.3 1.0

Reference:

J.Li, P.Brick, M.C.O'hare, T.Skarzynski, L.F.Lloyd, V.A.Curry, I.M.Clark, H.F.Bigg, B.L.Hazleman, T.E.Cawston, D.M.Blow. Structure of Full-Length Porcine Synovial Collagenase Reveals A C-Terminal Domain Containing A Calcium-Linked, Four-Bladed Beta-Propeller. Structure V. 3 541 1995.
ISSN: ISSN 0969-2126
PubMed: 8590015
DOI: 10.1016/S0969-2126(01)00188-5
Page generated: Sun Oct 13 00:53:54 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy