Atomistry » Zinc » PDB 1evr-1f62 » 1eyw
Atomistry »
  Zinc »
    PDB 1evr-1f62 »
      1eyw »

Zinc in PDB 1eyw: Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate

Enzymatic activity of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate

All present enzymatic activity of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate:
3.1.8.1;

Protein crystallography data

The structure of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate, PDB code: 1eyw was solved by H.M.Holden, M.M.Benning, F.M.Raushel, S.-B.Hong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.90
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 128.620, 92.330, 69.850, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Zinc Binding Sites:

The binding sites of Zinc atom in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate (pdb code 1eyw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate, PDB code: 1eyw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 1eyw

Go back to Zinc Binding Sites List in 1eyw
Zinc binding site 1 out of 2 in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:9.9
occ:1.00
NE2 A:HIS55 2.0 5.9 1.0
NE2 A:HIS57 2.1 12.1 1.0
OQ2 A:KCX169 2.2 10.3 1.0
OD2 A:ASP301 2.2 8.2 1.0
O A:HOH410 2.2 19.6 1.0
CD2 A:HIS55 2.9 10.4 1.0
CE1 A:HIS57 3.1 12.5 1.0
CX A:KCX169 3.1 9.4 1.0
CD2 A:HIS57 3.1 8.0 1.0
CG A:ASP301 3.1 13.9 1.0
CE1 A:HIS55 3.2 10.9 1.0
OD1 A:ASP301 3.4 13.0 1.0
OQ1 A:KCX169 3.5 12.6 1.0
ZN A:ZN402 3.5 13.6 1.0
CG2 A:VAL101 4.1 6.7 1.0
CG A:HIS55 4.1 7.4 1.0
NZ A:KCX169 4.2 11.3 1.0
ND1 A:HIS55 4.2 7.9 1.0
ND1 A:HIS57 4.2 8.7 1.0
C3 A:TEN403 4.2 13.4 0.7
CE1 A:HIS230 4.2 8.3 1.0
CG A:HIS57 4.2 10.4 1.0
NE2 A:HIS230 4.3 13.0 1.0
CB A:ASP301 4.4 5.7 1.0
C4 A:TEN403 4.6 11.2 0.7
O1 A:TEN403 4.6 31.3 0.7
CA A:ASP301 4.9 8.4 1.0

Zinc binding site 2 out of 2 in 1eyw

Go back to Zinc Binding Sites List in 1eyw
Zinc binding site 2 out of 2 in the Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with Bound Substrate Analog Triethylphosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:13.6
occ:1.00
OQ1 A:KCX169 1.9 12.6 1.0
ND1 A:HIS201 2.0 22.0 1.0
NE2 A:HIS230 2.1 13.0 1.0
O A:HOH410 2.5 19.6 1.0
CX A:KCX169 2.9 9.4 1.0
CE1 A:HIS201 2.9 22.8 1.0
CD2 A:HIS230 3.1 6.8 1.0
CE1 A:HIS230 3.1 8.3 1.0
CG A:HIS201 3.2 19.9 1.0
OQ2 A:KCX169 3.3 10.3 1.0
O1 A:TEN403 3.4 31.3 0.7
ZN A:ZN401 3.5 9.9 1.0
CB A:HIS201 3.6 8.8 1.0
NE2 A:HIS55 4.0 5.9 1.0
CE1 A:HIS55 4.0 10.9 1.0
NE2 A:HIS201 4.1 17.7 1.0
CG A:HIS230 4.2 8.9 1.0
ND1 A:HIS230 4.2 9.6 1.0
CD2 A:HIS201 4.2 23.4 1.0
NZ A:KCX169 4.2 11.3 1.0
OD1 A:ASP301 4.2 13.0 1.0
NE1 A:TRP131 4.3 9.5 1.0
CA A:HIS201 4.4 13.0 1.0
P1 A:TEN403 4.7 36.3 0.7
CE A:KCX169 4.8 15.3 1.0
OD2 A:ASP301 4.8 8.2 1.0
O4 A:TEN403 4.8 34.7 0.7
CD1 A:TRP131 4.9 6.1 1.0
CG A:ASP301 4.9 13.9 1.0
C3 A:TEN403 4.9 13.4 0.7

Reference:

M.M.Benning, S.B.Hong, F.M.Raushel, H.M.Holden. The Binding of Substrate Analogs to Phosphotriesterase. J.Biol.Chem. V. 275 30556 2000.
ISSN: ISSN 0021-9258
PubMed: 10871616
DOI: 10.1074/JBC.M003852200
Page generated: Wed Dec 16 02:48:50 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy