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Zinc in PDB 1eb3: Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex

Enzymatic activity of Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex

All present enzymatic activity of Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex:
4.2.1.24;

Protein crystallography data

The structure of Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex, PDB code: 1eb3 was solved by P.T.Erskine, L.Coates, R.Newbold, A.A.Brindley, F.Stauffer, S.P.Wood, M.J.Warren, J.B.Cooper, P.M.Shoolingin-Jordan, R.Neier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.30 / 1.75
Space group I 4 2 2
Cell size a, b, c (Å), α, β, γ (°) 104.300, 104.300, 167.200, 90.00, 90.00, 90.00
R / Rfree (%) 23.9 / 30.8

Zinc Binding Sites:

The binding sites of Zinc atom in the Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex (pdb code 1eb3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex, PDB code: 1eb3:

Zinc binding site 1 out of 1 in 1eb3

Go back to Zinc Binding Sites List in 1eb3
Zinc binding site 1 out of 1 in the Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Yeast 5-Aminolaevulinic Acid Dehydratase 4,7-Dioxosebacic Acid Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1342

b:24.9
occ:1.00
O A:HOH2402 2.0 24.7 1.0
SG A:CYS133 2.3 23.2 1.0
SG A:CYS135 2.3 26.6 1.0
SG A:CYS143 2.3 24.6 1.0
CB A:CYS135 3.3 17.0 1.0
CB A:CYS143 3.3 20.1 1.0
CB A:CYS133 3.3 10.5 1.0
CA A:CYS143 3.8 20.5 1.0
O A:HOH2281 4.0 21.5 1.0
N A:CYS135 4.0 24.2 1.0
O A:HOH2248 4.1 22.8 1.0
OG A:SER179 4.2 24.0 1.0
CA A:CYS135 4.3 22.6 1.0
O A:SER179 4.3 20.8 1.0
O A:HOH2251 4.5 24.4 1.0
O A:HOH2401 4.5 34.0 1.0
N A:CYS143 4.6 25.7 1.0
C8 A:DSB1341 4.6 39.7 1.0
CA A:CYS133 4.7 13.5 1.0
N A:LEU134 4.7 16.4 1.0
CA A:ASP180 4.8 20.0 1.0
C A:SER179 4.8 18.5 1.0
C A:CYS143 5.0 28.0 1.0
NE A:ARG232 5.0 36.6 1.0

Reference:

P.T.Erskine, L.Coates, R.Newbold, A.A.Brindley, F.Stauffer, S.P.Wood, M.J.Warren, J.B.Cooper, P.M.Shoolingin-Jordan, R.Neier. The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors Febs Lett. V. 503 196 2001.
ISSN: ISSN 0014-5793
PubMed: 11513881
DOI: 10.1016/S0014-5793(01)02721-1
Page generated: Wed Dec 16 02:48:07 2020

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