Zinc in PDB 1dvp: Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction

The structure of Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction, PDB code: 1dvp was solved by Y.Mao, A.Nickitenko, X.Duan, T.E.Lloyd, M.N.Wu, H.Bellen, F.A.Quiocho, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	116.706, 69.665, 41.799, 90.00, 94.77, 90.00
R / Rfree (%)	21.5 / 25.4

The binding sites of Zinc atom in the Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction (pdb code 1dvp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction, PDB code: 1dvp:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:19.2 occ:1.00 SG A:CYS188 2.2 13.5 1.0 SG A:CYS191 2.4 20.2 1.0 SG A:CYS167 2.5 18.7 1.0 SG A:CYS164 2.5 17.1 1.0 CB A:CYS191 3.2 19.1 1.0 CB A:CYS164 3.3 17.9 1.0 CB A:CYS167 3.4 19.5 1.0 CB A:CYS188 3.5 15.1 1.0 N A:CYS167 3.8 20.1 1.0 N A:CYS188 3.9 14.8 1.0 N A:CYS191 4.1 19.3 1.0 CG1 A:VAL169 4.2 18.1 1.0 O A:HOH495 4.2 32.9 1.0 CA A:CYS167 4.2 19.7 1.0 CA A:CYS188 4.2 15.4 1.0 CA A:CYS191 4.2 19.4 1.0 CA A:CYS164 4.7 18.2 1.0 O A:CYS188 4.8 15.5 1.0 C A:CYS188 4.8 15.7 1.0 O A:HOH444 4.8 29.2 1.0 CB A:ARG166 4.9 20.6 1.0 C A:CYS167 4.9 19.6 1.0 C A:ARG166 5.0 20.1 1.0 C A:PHE187 5.0 15.3 1.0 N A:ARG168 5.0 19.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:20.3 occ:1.00 SG A:CYS180 2.3 17.8 1.0 SG A:CYS183 2.4 17.8 1.0 SG A:CYS213 2.4 24.8 1.0 SG A:CYS210 2.4 21.8 1.0 CB A:CYS213 3.2 25.3 1.0 CB A:CYS180 3.2 16.2 1.0 CB A:CYS183 3.4 17.6 1.0 CB A:CYS210 3.4 20.9 1.0 N A:CYS183 3.7 18.6 1.0 N A:CYS210 3.9 20.6 1.0 CZ A:PHE187 4.0 15.4 1.0 CA A:CYS183 4.1 18.3 1.0 O A:HOH482 4.2 27.9 1.0 CE1 A:PHE187 4.2 15.1 1.0 CA A:CYS210 4.2 20.9 1.0 N A:CYS213 4.3 25.4 1.0 CA A:CYS213 4.3 26.0 1.0 O A:HOH481 4.5 56.8 1.0 CB A:ASN182 4.5 20.0 1.0 CA A:CYS180 4.6 16.5 1.0 C A:ASN182 4.6 18.8 1.0 O A:CYS210 4.8 20.9 1.0 C A:CYS210 4.8 21.4 1.0 CA A:ASN182 4.9 18.9 1.0 N A:ASN182 4.9 18.2 1.0 C A:CYS183 5.0 18.1 1.0 C A:VAL209 5.0 20.6 1.0

Y.Mao, A.Nickitenko, X.Duan, T.E.Lloyd, M.N.Wu, H.Bellen, F.A.Quiocho. Crystal Structure of the Vhs and Fyve Tandem Domains of Hrs, A Protein Involved in Membrane Trafficking and Signal Transduction. Cell(Cambridge,Mass.) V. 100 447 2000.
ISSN: ISSN 0092-8674
PubMed: 10693761
DOI: 10.1016/S0092-8674(00)80680-7