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Zinc in PDB 1d8y: Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna

Enzymatic activity of Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna

All present enzymatic activity of Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna:
2.7.7.7;

Protein crystallography data

The structure of Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna, PDB code: 1d8y was solved by M.Teplova, S.T.Wallace, V.Tereshko, G.Minasov, A.M.Simons, P.D.Cook, M.Manoharan, M.Egli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.08
Space group P 43
Cell size a, b, c (Å), α, β, γ (°) 101.880, 101.880, 85.180, 90.00, 90.00, 90.00
R / Rfree (%) 21.7 / 23.3

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna (pdb code 1d8y). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna, PDB code: 1d8y:

Zinc binding site 1 out of 1 in 1d8y

Go back to Zinc Binding Sites List in 1d8y
Zinc binding site 1 out of 1 in the Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Complex of Dna Polymerase I Klenow Fragment with Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn3

b:70.0
occ:1.00
OE2 A:GLU905 2.3 38.0 1.0
NE2 A:HIS901 2.4 35.2 1.0
CD A:GLU905 2.9 38.0 1.0
OE1 A:GLU905 3.1 34.8 1.0
CD2 A:HIS901 3.3 36.4 1.0
CE1 A:HIS901 3.3 33.7 1.0
CG A:GLU905 4.0 36.4 1.0
O A:HOH1158 4.1 49.5 1.0
ND1 A:HIS901 4.4 35.3 1.0
CG A:HIS901 4.4 33.5 1.0
O A:HOH1084 4.9 61.7 1.0

Reference:

M.Teplova, S.T.Wallace, V.Tereshko, G.Minasov, A.M.Symons, P.D.Cook, M.Manoharan, M.Egli. Structural Origins of the Exonuclease Resistance of A Zwitterionic Rna. Proc.Natl.Acad.Sci.Usa V. 96 14240 1999.
ISSN: ISSN 0027-8424
PubMed: 10588690
DOI: 10.1073/PNAS.96.25.14240
Page generated: Sat Oct 12 23:34:19 2024

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