Zinc in PDB 1cyy: Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form

All present enzymatic activity of Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form:
5.99.1.2;

The structure of Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form, PDB code: 1cyy was solved by H.Feinberg, C.Lima, A.Mondragon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.97 / 2.15
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	113.850, 113.850, 233.870, 90.00, 90.00, 120.00
R / Rfree (%)	22.9 / 28.2

The binding sites of Zinc atom in the Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form (pdb code 1cyy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form, PDB code: 1cyy:

Zinc binding site 1 out of 1 in the Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the 30 kDa Fragment of E. Coli Dna Topoisomerase I. Hexagonal Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:34.9 occ:1.00 NE2 A:HIS365 2.1 40.0 1.0 CD2 A:HIS365 2.9 39.3 1.0 CE1 A:HIS365 3.2 40.2 1.0 O A:HOH1183 3.7 58.1 1.0 O A:HOH1113 3.8 41.4 1.0 CG A:HIS365 4.1 39.6 1.0 ND1 A:HIS365 4.2 39.5 1.0 OD1 A:ASP323 4.2 36.1 1.0 O A:HOH1143 4.3 37.6 1.0 O A:HOH1173 4.8 52.1 1.0 OD2 A:ASP323 4.9 34.7 1.0 CG A:ASP323 5.0 34.5 1.0

H.Feinberg, C.D.Lima, A.Mondragon. Conformational Changes in E. Coli Dna Topoisomerase I. Nat.Struct.Biol. V. 6 918 1999.
ISSN: ISSN 1072-8368
PubMed: 10504724
DOI: 10.1038/13283