Zinc in PDB 1cu1: Crystal Structure of An Enzyme Complex From Hepatitis C Virus

The structure of Crystal Structure of An Enzyme Complex From Hepatitis C Virus, PDB code: 1cu1 was solved by N.Yao, P.C.Weber, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	91.360, 110.510, 141.200, 90.00, 90.00, 90.00
R / Rfree (%)	20 / 26

The binding sites of Zinc atom in the Crystal Structure of An Enzyme Complex From Hepatitis C Virus (pdb code 1cu1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of An Enzyme Complex From Hepatitis C Virus, PDB code: 1cu1:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of An Enzyme Complex From Hepatitis C Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of An Enzyme Complex From Hepatitis C Virus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn999 b:39.5 occ:1.00 SG A:CYS99 2.3 31.9 1.0 SG A:CYS145 2.4 26.2 1.0 SG A:CYS97 2.4 28.0 1.0 O A:HOH998 2.4 14.6 1.0 CB A:CYS145 3.2 27.3 1.0 CB A:CYS99 3.2 28.4 1.0 CB A:CYS97 3.2 26.5 1.0 N A:CYS99 3.4 30.5 1.0 CA A:CYS99 3.8 27.0 1.0 CA A:CYS97 3.8 26.4 1.0 N A:THR98 4.0 31.4 1.0 C A:CYS97 4.2 28.6 1.0 N A:GLY100 4.3 34.4 1.0 CB A:SER147 4.3 35.9 1.0 OG A:SER147 4.3 43.9 1.0 C A:CYS99 4.4 28.8 1.0 CB A:HIS149 4.6 28.7 1.0 C A:THR98 4.6 33.8 1.0 CA A:CYS145 4.6 26.0 1.0 N A:SER147 4.8 33.2 1.0 N A:SER101 4.9 31.0 1.0 CA A:THR98 4.9 29.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of An Enzyme Complex From Hepatitis C Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of An Enzyme Complex From Hepatitis C Virus within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1999 b:63.6 occ:1.00 SG B:CYS1145 2.3 50.6 1.0 SG B:CYS1097 2.3 53.7 1.0 SG B:CYS1099 2.6 57.8 1.0 CB B:CYS1145 3.2 46.7 1.0 CB B:CYS1097 3.2 49.6 1.0 OG B:SER1147 3.3 65.9 1.0 CB B:CYS1099 3.4 53.5 1.0 N B:CYS1099 3.7 54.6 1.0 CA B:CYS1097 3.7 50.6 1.0 N B:THR1098 3.7 56.6 1.0 CA B:CYS1099 4.1 54.6 1.0 C B:CYS1097 4.2 53.5 1.0 CB B:HIS1149 4.3 53.9 1.0 CB B:SER1147 4.4 61.1 1.0 ND1 B:HIS1149 4.4 62.6 1.0 C B:THR1098 4.6 56.9 1.0 CA B:CYS1145 4.7 43.8 1.0 N B:GLY1100 4.7 56.6 1.0 C B:CYS1099 4.8 55.0 1.0 CA B:THR1098 4.8 56.0 1.0 CG B:HIS1149 4.8 59.7 1.0 N B:SER1147 4.9 56.0 1.0

N.Yao, P.Reichert, S.S.Taremi, W.W.Prosise, P.C.Weber. Molecular Views of Viral Polyprotein Processing Revealed By the Crystal Structure of the Hepatitis C Virus Bifunctional Protease-Helicase. Structure Fold.Des. V. 7 1353 1999.
ISSN: ISSN 0969-2126
PubMed: 10574797
DOI: 10.1016/S0969-2126(00)80025-8