Zinc in PDB 1cko: Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg

All present enzymatic activity of Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg:
2.7.7.50;

The structure of Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg, PDB code: 1cko was solved by K.Hakansson, D.B.Wigley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 3.10
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	78.476, 164.013, 103.502, 90.00, 90.00, 90.00
R / Rfree (%)	23.3 / 31.4

The binding sites of Zinc atom in the Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg (pdb code 1cko). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg, PDB code: 1cko:

Zinc binding site 1 out of 1 in the Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Mrna Capping Enzyme in Complex with the Cap Analog Gpppg within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn888 b:0.8 occ:1.00 NE2 A:HIS195 2.9 0.8 1.0 CE1 A:HIS195 3.2 0.2 1.0 CD2 A:HIS195 4.1 0.4 1.0 ND1 A:HIS195 4.4 0.7 1.0 CG A:GLU194 4.5 0.4 1.0 CG A:HIS195 4.9 0.3 1.0 OE2 A:GLU194 4.9 0.8 1.0

K.Hakansson, D.B.Wigley. Structure of A Complex Between A Cap Analogue and Mrna Guanylyl Transferase Demonstrates the Structural Chemistry of Rna Capping. Proc.Natl.Acad.Sci.Usa V. 95 1505 1998.
ISSN: ISSN 0027-8424
PubMed: 9465045
DOI: 10.1073/PNAS.95.4.1505