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Zinc in PDB 1ciz: X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity
Enzymatic activity of X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity
All present enzymatic activity of X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity:
3.4.24.17;
3.4.24.17;
Protein crystallography data
The structure of X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity, PDB code: 1ciz
was solved by
A.G.Pavlovsky,
M.G.Williams,
Q.-Z.Ye,
D.F.Ortwine,
C.F.Purchase Ii,
A.D.White,
V.Dhanaraj,
B.D.Roth,
L.L.Johnson,
D.Hupe,
C.Humblet,
T.L.Blundell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 8.00 / 1.64 |
| Space group | P 41 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 69.370, 69.370, 74.400, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 20.9 / 24.5 |
Other elements in 1ciz:
The structure of X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity also contains other interesting chemical elements:
| Calcium | (Ca) | 3 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity
(pdb code 1ciz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity, PDB code: 1ciz:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity, PDB code: 1ciz:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 1ciz
Go back to
Zinc Binding Sites List in 1ciz
Zinc binding site 1 out
of 2 in the X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity within 5.0Å range:
|
Zinc binding site 2 out of 2 in 1ciz
Go back to
Zinc Binding Sites List in 1ciz
Zinc binding site 2 out
of 2 in the X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of X-Ray Structure of Human Stromelysin Catalytic Domain Complexes with Non-Peptide Inhibitors: Implication For Inhibitor Selectivity within 5.0Å range:
|
Reference:
A.G.Pavlovsky,
M.G.Williams,
Q.Z.Ye,
D.F.Ortwine,
C.F.Purchase Ii,
A.D.White,
V.Dhanaraj,
B.D.Roth,
L.L.Johnson,
D.Hupe,
C.Humblet,
T.L.Blundell.
X-Ray Structure of Human Stromelysin Catalytic Domain Complexed with Nonpeptide Inhibitors: Implications For Inhibitor Selectivity. Protein Sci. V. 8 1455 1999.
ISSN: ISSN 0961-8368
PubMed: 10422833
Page generated: Sat Oct 12 23:09:58 2024
ISSN: ISSN 0961-8368
PubMed: 10422833
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