Atomistry » Zinc » PDB 9im0-9j9s » 9j3p
Atomistry »
  Zinc »
    PDB 9im0-9j9s »
      9j3p »

Zinc in PDB 9j3p: Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group

Protein crystallography data

The structure of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group, PDB code: 9j3p was solved by A.S.Belousov, D.V.Chistyakov, V.E.Baksheeva, T.K.Bulgakov, S.S.Bukhdruker, A.A.Zamyatnin, D.V.Zinchenko, P.O.Tsvetkov, S.E.Permyakov, E.Y.Zernii, V.I.Borshchevskiy, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.95 / 2.10
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 74.234, 131.567, 227.831, 90, 90, 90
R / Rfree (%) 21.7 / 25.1

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group (pdb code 9j3p). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group, PDB code: 9j3p:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7;

Zinc binding site 1 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 1 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn501

b:59.2
occ:0.96
ND1 A:HIS381 2.0 55.6 1.0
O A:HOH680 2.2 63.1 1.0
HB3 A:HIS381 2.8 57.4 1.0
CG A:HIS381 3.0 60.1 1.0
CE1 A:HIS381 3.0 56.3 1.0
HA A:HIS381 3.2 56.5 1.0
HE1 A:HIS381 3.2 56.3 1.0
CB A:HIS381 3.2 57.4 1.0
CA A:HIS381 3.7 56.5 1.0
O A:HIS381 3.9 56.7 1.0
CD2 A:HIS381 4.1 57.0 1.0
NE2 A:HIS381 4.1 57.1 1.0
HB2 A:HIS381 4.1 57.4 1.0
C A:HIS381 4.3 61.6 1.0
HE2 A:HIS381 4.9 57.1 1.0
HD2 A:HIS381 4.9 57.0 1.0
N A:HIS381 5.0 59.5 1.0

Zinc binding site 2 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 2 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn501

b:75.7
occ:1.00
OD2 C:ASP44 2.0 70.7 1.0
NE2 C:HIS299 2.0 72.9 1.0
OE2 B:GLU236 2.0 83.4 1.0
OE1 B:GLU236 2.6 80.2 1.0
OD1 C:ASP44 2.6 74.5 1.0
CG C:ASP44 2.6 72.8 1.0
CD B:GLU236 2.6 81.3 1.0
CD2 C:HIS299 2.8 71.8 1.0
HD2 C:HIS299 2.9 71.7 1.0
HD3 C:ARG303 3.1 74.8 1.0
CE1 C:HIS299 3.1 70.9 1.0
HD2 C:ARG303 3.2 74.8 1.0
HE1 C:HIS299 3.4 70.9 1.0
CD C:ARG303 3.6 74.8 1.0
HB3 C:PHE46 3.7 67.8 1.0
HB2 C:PHE46 3.8 67.8 1.0
HD2 C:PRO45 3.9 86.1 1.0
H C:PHE46 3.9 72.5 1.0
CG C:HIS299 4.1 70.7 1.0
CB C:ASP44 4.1 73.9 1.0
CG B:GLU236 4.1 77.2 1.0
ND1 C:HIS299 4.1 70.8 1.0
NE C:ARG303 4.1 79.3 1.0
HE C:ARG303 4.2 79.3 1.0
CB C:PHE46 4.2 67.8 1.0
HB2 C:ASP44 4.4 73.9 1.0
HG2 B:GLU236 4.4 77.2 1.0
HG3 B:GLU236 4.5 77.2 1.0
HA C:ASP44 4.6 77.8 1.0
HB3 C:ASP44 4.6 73.9 1.0
N C:PHE46 4.7 72.6 1.0
CD C:PRO45 4.7 86.1 1.0
CA C:ASP44 4.8 77.8 1.0
HG3 C:ARG303 4.8 68.5 1.0
HB3 B:GLU236 4.8 78.8 1.0
CG C:ARG303 4.9 68.5 1.0
HD1 C:HIS299 4.9 70.8 1.0
N C:PRO45 5.0 82.3 1.0
H C:PHE47 5.0 66.6 1.0
CZ C:ARG303 5.0 79.2 1.0

Zinc binding site 3 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 3 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn502

b:73.6
occ:0.72
NE2 C:HIS381 2.0 77.4 1.0
HE1 C:HIS381 2.4 77.3 1.0
CE1 C:HIS381 2.4 77.3 1.0
CD2 C:HIS381 3.2 75.8 1.0
ND1 C:HIS381 3.6 77.5 1.0
HD2 C:HIS381 3.7 75.8 1.0
CG C:HIS381 4.0 74.3 1.0
HD1 C:HIS381 4.2 77.5 1.0
HD23 C:LEU382 4.9 81.9 1.0

Zinc binding site 4 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 4 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn501

b:71.3
occ:1.00
ND1 D:HIS381 2.0 75.7 1.0
ND1 B:HIS381 2.2 69.7 1.0
HA D:HIS381 2.9 88.8 1.0
CG D:HIS381 2.9 78.2 1.0
CE1 D:HIS381 2.9 72.5 1.0
HB3 D:HIS381 3.0 80.4 1.0
CE1 B:HIS381 3.1 70.3 1.0
HE1 D:HIS381 3.2 72.5 1.0
HE1 B:HIS381 3.2 70.3 1.0
CG B:HIS381 3.2 69.2 1.0
CB D:HIS381 3.3 80.4 1.0
HB2 B:HIS381 3.4 66.4 1.0
HB3 B:HIS381 3.4 66.4 1.0
CA D:HIS381 3.5 88.8 1.0
CB B:HIS381 3.6 66.4 1.0
O D:ALA380 3.9 84.7 1.0
NE2 D:HIS381 4.0 78.2 1.0
CD2 D:HIS381 4.0 87.9 1.0
NE2 B:HIS381 4.2 69.3 1.0
H D:LEU382 4.2 96.2 0.5
H D:LEU382 4.2 96.2 0.5
HB2 D:HIS381 4.2 80.4 1.0
CD2 B:HIS381 4.3 67.4 1.0
N D:HIS381 4.5 99.7 1.0
C D:HIS381 4.6 90.5 1.0
N D:LEU382 4.7 96.2 1.0
C D:ALA380 4.7 90.7 1.0
HE2 D:HIS381 4.8 78.2 1.0
HD2 D:HIS381 4.9 87.9 1.0
HE2 B:HIS381 4.9 69.3 1.0
HG B:LEU382 5.0 62.1 1.0

Zinc binding site 5 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 5 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn501

b:74.5
occ:1.00
NE2 E:HIS299 2.1 76.4 1.0
OD1 E:ASP44 2.1 75.6 1.0
O E:HOH615 2.2 75.3 1.0
OD2 E:ASP44 2.3 79.7 1.0
CG E:ASP44 2.5 74.1 1.0
HD2 E:HIS299 2.6 78.8 1.0
CD2 E:HIS299 2.7 78.8 1.0
CE1 E:HIS299 3.3 73.5 1.0
HG3 E:ARG303 3.6 68.6 1.0
HB3 E:PHE46 3.7 67.6 1.0
HD2 E:PRO45 3.7 81.2 1.0
HE1 E:HIS299 3.8 73.5 1.0
H E:PHE46 3.8 72.6 1.0
HB2 E:PHE46 3.8 67.6 1.0
CG E:HIS299 4.0 77.4 1.0
CB E:ASP44 4.0 77.0 1.0
HD3 E:ARG303 4.1 66.9 1.0
HE E:ARG303 4.1 67.9 1.0
CB E:PHE46 4.2 67.6 1.0
ND1 E:HIS299 4.3 74.7 1.0
NE E:ARG303 4.3 67.9 1.0
CG E:ARG303 4.4 68.6 1.0
HB2 E:ASP44 4.5 77.0 1.0
CD E:ARG303 4.5 66.9 1.0
HA E:ASP44 4.5 82.3 1.0
HB3 E:ASP44 4.5 77.0 1.0
N E:PHE46 4.6 72.6 1.0
CD E:PRO45 4.6 81.2 1.0
CA E:ASP44 4.7 82.3 1.0
HG2 E:ARG303 4.8 68.6 1.0
HE2 E:PHE47 4.9 68.7 1.0
N E:PRO45 4.9 79.4 1.0
C E:ASP44 5.0 76.7 1.0

Zinc binding site 6 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 6 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn502

b:85.8
occ:0.52
NE2 E:HIS381 2.1 92.3 1.0
O E:HOH640 2.2 82.9 1.0
HD2 E:HIS381 2.8 85.3 1.0
CD2 E:HIS381 2.8 85.3 1.0
CE1 E:HIS381 3.3 85.5 1.0
HE1 E:HIS381 3.6 85.5 1.0
CG E:HIS381 4.0 83.8 1.0
ND1 E:HIS381 4.2 84.5 1.0

Zinc binding site 7 out of 7 in 9j3p

Go back to Zinc Binding Sites List in 9j3p
Zinc binding site 7 out of 7 in the Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Human Pigment Epithelium-Derived Factor with Zinc Ions Crystallized in P2(1)2(1)2(1) Space Group within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn503

b:82.1
occ:0.57
ND1 E:HIS105 2.1 72.5 1.0
O E:HOH651 2.2 79.8 1.0
O E:HOH661 2.2 94.2 1.0
CE1 E:HIS105 3.0 76.5 1.0
HE1 E:HIS105 3.1 76.5 1.0
CG E:HIS105 3.1 67.3 1.0
HB3 E:HIS105 3.3 65.1 1.0
CB E:HIS105 3.6 65.1 1.0
HB2 E:HIS105 3.7 65.1 1.0
NE2 E:HIS105 4.1 74.2 1.0
HG2 E:GLU101 4.2 72.9 1.0
CD2 E:HIS105 4.2 68.1 1.0
HB3 E:TYR110 4.3 65.3 1.0
HD2 E:TYR110 4.3 65.0 1.0
HB2 E:TYR110 4.6 65.3 1.0
HA E:SER102 4.7 70.7 1.0
OE1 E:GLU101 4.9 75.8 1.0
HE2 E:HIS105 4.9 74.2 1.0
CB E:TYR110 4.9 65.3 1.0

Reference:

D.V.Chistyakov, M.P.Shevelyova, E.N.Iomdina, V.E.Baksheeva, L.Wu, N.G.Shebardina, A.M.Moysenovich, T.K.Bulgakov, S.Y.Petrov, V.V.Tiulina, E.I.Pogodina, O.S.Gancharova, A.S.Belousov, O.M.Filippova, A.V.Baldin, S.V.Goriainov, A.I.Nikolskaya, A.O.Zalevsky, A.A.Deviatkin, A.A.Vologzhannikova, N.V.Gorokhovets, E.A.Litus, A.A.Zamyatnin, S.V.Komarov, F.Devred, M.G.Sergeeva, A.A.Zamyatnin Jr, I.I.Senin, D.V.Zinchenko, P.O.Tsvetkov, V.I.Borshchevskiy, S.E.Permyakov, E.Y.Zernii. Zinc-Mediated Mechanism of Neurodegeneration in Glaucoma: A Role of Pigment Epithelium-Derived Factor To Be Published.
Page generated: Fri Aug 22 18:19:19 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy