Zinc in PDB 9h1z: Cryo-Em Structure of Human OAS2 Dimer

All present enzymatic activity of Cryo-Em Structure of Human OAS2 Dimer:
2.7.7.84;

The binding sites of Zinc atom in the Cryo-Em Structure of Human OAS2 Dimer (pdb code 9h1z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Human OAS2 Dimer, PDB code: 9h1z:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Human OAS2 Dimer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human OAS2 Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:192.5 occ:1.00 SG B:CYS652 2.3 139.5 1.0 NE2 A:HIS654 2.5 114.8 1.0 CE1 B:HIS654 2.8 114.5 1.0 CE1 A:HIS654 3.1 121.2 1.0 SG A:CYS652 3.2 141.1 1.0 CB B:CYS652 3.4 115.8 1.0 CD2 A:HIS654 3.7 118.3 1.0 NE2 B:HIS654 3.7 121.5 1.0 ND1 B:HIS654 3.8 122.0 1.0 CA B:CYS652 3.9 110.0 1.0 CB A:CYS652 3.9 117.1 1.0 ND1 A:HIS654 4.3 115.1 1.0 O A:LYS560 4.6 167.5 1.0 N B:CYS652 4.6 116.8 1.0 CG A:HIS654 4.7 113.6 1.0 CA A:CYS652 4.7 109.0 1.0 CG A:LEU655 4.8 114.0 1.0 CD1 A:LEU655 4.8 123.4 1.0 CA B:GLY561 4.9 152.5 1.0 CD2 B:HIS654 4.9 114.7 1.0 CG B:HIS654 5.0 115.5 1.0

V.R.Merold, K.Lammens, C.C.De Oliveira Mann. Structural Basis For OAS2 Regulation and Its Antiviral Function Mol.Cell 2025.
ISSN: ISSN 1097-2765
DOI: 10.1016/J.MOLCEL.2025.05.001