Zinc in PDB 9csj: Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution.

The structure of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution., PDB code: 9csj was solved by I.Griswold-Prenner, Y.Dou, A.Jennings, F.Kayser, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.34 / 2.33
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	85.96, 85.96, 135.9, 90, 90, 90
R / Rfree (%)	22 / 26.9

The structure of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. also contains other interesting chemical elements:

Magnesium	(Mg)	3 atoms
Chlorine	(Cl)	12 atoms

The binding sites of Zinc atom in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. (pdb code 9csj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution., PDB code: 9csj:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:35.7 occ:1.00 OE1 A:GLU70 2.0 34.7 1.0 CL A:CL305 2.1 36.9 1.0 NE2 A:HIS8 2.1 30.8 1.0 CL A:CL310 2.2 46.4 1.0 CD A:GLU70 2.7 35.6 1.0 OE2 A:GLU70 2.7 41.9 1.0 CD2 A:HIS8 3.1 31.1 1.0 CE1 A:HIS8 3.1 32.2 1.0 O A:HOH459 4.0 36.9 1.0 CG A:GLU70 4.1 33.0 1.0 CG2 A:VAL10 4.1 28.7 1.0 CB A:ALA203 4.1 28.9 1.0 ND1 A:HIS8 4.2 29.9 1.0 CG A:HIS8 4.2 30.3 1.0 CB A:GLU70 4.6 31.3 1.0 O4 A:PEG312 4.8 57.2 1.0 NZ A:LYS55 4.9 41.8 1.0 C4 A:PEG312 4.9 55.7 1.0

Zinc binding site 2 out of 5 in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:30.3 occ:1.00 NE2 A:HIS66 1.9 31.2 1.0 CL A:CL309 2.1 32.3 1.0 CL A:CL308 2.3 36.1 1.0 CE1 A:HIS66 2.8 31.6 1.0 CD2 A:HIS66 3.1 30.8 1.0 ND1 A:HIS66 4.0 29.4 1.0 CG A:HIS66 4.1 29.5 1.0 O A:HOH441 4.2 31.2 1.0 N A:ASP136 4.4 32.5 1.0 C A:SER135 4.4 35.2 1.0 O A:PHE60 4.5 28.6 1.0 CA A:ASP136 4.6 30.5 1.0 CA A:SER135 4.7 37.0 1.0 O A:SER135 4.8 35.6 1.0 CA A:GLY61 4.9 27.1 1.0 C A:PHE60 4.9 27.7 1.0

Zinc binding site 3 out of 5 in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn304 b:29.3 occ:1.00 NE2 A:HIS291 1.9 31.6 1.0 CL A:CL306 2.1 32.0 1.0 CL A:CL307 2.3 33.9 1.0 CD2 A:HIS291 2.9 32.3 1.0 CE1 A:HIS291 3.0 31.7 1.0 NE1 A:TRP287 3.4 33.1 1.0 CD1 A:TRP287 4.0 32.0 1.0 CE2 A:TRP287 4.0 32.7 1.0 CG A:HIS291 4.0 31.2 1.0 ND1 A:HIS291 4.0 31.1 1.0 CZ2 A:TRP287 4.4 33.0 1.0 CG A:TRP287 4.8 31.0 1.0 CD2 A:TRP287 4.9 30.8 1.0

Zinc binding site 4 out of 5 in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn304 b:35.6 occ:1.00 NE2 B:HIS8 2.1 33.0 1.0 CL B:CL305 2.1 35.5 1.0 OE2 B:GLU70 2.2 37.9 1.0 CL B:CL306 2.3 48.8 1.0 OE1 B:GLU70 2.4 38.7 1.0 CD B:GLU70 2.6 36.4 1.0 CD2 B:HIS8 3.0 33.0 1.0 CE1 B:HIS8 3.1 33.1 1.0 CG B:GLU70 4.0 34.8 1.0 O B:HOH516 4.1 39.3 1.0 CG2 B:VAL10 4.1 29.1 1.0 CB B:ALA203 4.1 29.7 1.0 CG B:HIS8 4.2 32.0 1.0 ND1 B:HIS8 4.2 31.7 1.0 CB B:GLU70 4.6 32.5 1.0

Zinc binding site 5 out of 5 in the Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of Human Glyoxalase Domain-Containing Protein 4 (GLOD4) at 2.33 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn302 b:57.8 occ:0.80 OE1 C:GLU70 1.9 78.2 1.0 NE2 C:HIS8 2.1 64.6 1.0 CL C:CL303 2.2 68.8 1.0 O C:HOH408 2.3 64.5 1.0 O C:HOH442 2.6 56.9 1.0 CD C:GLU70 3.0 69.5 1.0 CE1 C:HIS8 3.0 61.1 1.0 CD2 C:HIS8 3.1 65.8 1.0 OE2 C:GLU70 3.4 73.5 1.0 O C:HOH424 3.9 41.6 1.0 ND1 C:HIS8 4.1 62.3 1.0 CG C:HIS8 4.1 63.9 1.0 NH1 C:ARG201 4.2 73.3 1.0 CG C:GLU70 4.2 66.8 1.0 CG2 C:VAL10 4.2 71.8 1.0 CB C:ALA203 4.2 66.8 1.0 NE C:ARG201 4.3 68.8 1.0 CB C:GLU70 4.7 59.9 1.0 CZ C:ARG201 4.8 75.3 1.0

I.Griswold-Prenner, F.Kayser. Crystal Structure of Apo-Glyoxalase Domain-Containing Protein 4 (Apo-GLOD4) at 2.33 A Resolution. To Be Published.