Zinc in PDB 9bf8: Sars-Cov-2 Papain-Like Protease (Plpro) Untagged Crystal Structure

The structure of Sars-Cov-2 Papain-Like Protease (Plpro) Untagged Crystal Structure, PDB code: 9bf8 was solved by A.I.Al-Homoudi, J.Engel, J.S.Brunzelle, N.Gavande, L.C.Kovari, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.60 / 1.85
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	82.342, 82.342, 136.407, 90, 90, 120
R / Rfree (%)	17.7 / 20.2

The binding sites of Zinc atom in the Sars-Cov-2 Papain-Like Protease (Plpro) Untagged Crystal Structure (pdb code 9bf8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Sars-Cov-2 Papain-Like Protease (Plpro) Untagged Crystal Structure, PDB code: 9bf8:

Zinc binding site 1 out of 1 in the Sars-Cov-2 Papain-Like Protease (Plpro) Untagged Crystal Structure


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Papain-Like Protease (Plpro) Untagged Crystal Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:46.3 occ:1.00 SG A:CYS226 2.3 45.4 1.0 SG A:CYS189 2.4 42.1 1.0 SG A:CYS192 2.4 50.2 1.0 SG A:CYS224 2.4 48.1 1.0 CB A:CYS226 3.2 49.9 1.0 CB A:CYS189 3.3 47.8 1.0 CB A:CYS224 3.4 39.7 1.0 CB A:CYS192 3.6 48.2 1.0 N A:CYS192 3.8 46.3 1.0 N A:CYS226 4.0 50.4 1.0 CA A:CYS226 4.2 48.4 1.0 CB A:THR191 4.2 46.0 1.0 CA A:CYS192 4.4 49.0 1.0 O A:HOH826 4.6 43.9 1.0 CA A:CYS224 4.7 42.5 1.0 CA A:CYS189 4.7 47.6 1.0 C A:THR191 4.7 48.7 1.0 CA A:THR191 4.8 46.0 1.0 N A:THR191 4.8 45.3 1.0 N A:THR225 4.8 48.9 1.0 CG2 A:THR191 4.9 41.5 1.0 CB A:LYS228 4.9 43.1 1.0 C A:CYS224 4.9 48.9 1.0 OG1 A:THR191 4.9 48.9 1.0 C A:CYS226 4.9 53.0 1.0

A.I.Al-Homoudi, J.Engel, M.D.Muczynski, J.S.Brunzelle, N.S.Gavande, L.C.Kovari. Human Structural Homologues of Sars-Cov-2 Pl Pro As Anti-Targets: A Strategic Panel Analysis. Micropubl Biol V.2025 2025.
ISSN: ISSN 2578-9430
PubMed: 40297819
DOI: 10.17912/MICROPUB.BIOLOGY.001418