Zinc in PDB 8t12: Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered.

The binding sites of Zinc atom in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered. (pdb code 8t12). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered., PDB code: 8t12:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:157.7 occ:1.00 NE2 B:HIS714 2.0 89.8 1.0 NE2 B:HIS712 2.0 118.7 1.0 SG B:CYS728 2.3 111.8 1.0 SG B:CYS847 2.3 121.4 1.0 CD2 B:HIS712 2.9 118.1 1.0 CD2 B:HIS714 3.0 88.9 1.0 CE1 B:HIS714 3.1 88.4 1.0 CE1 B:HIS712 3.1 117.8 1.0 CB B:CYS728 3.4 106.6 1.0 CB B:CYS847 3.7 119.0 1.0 CG B:HIS712 4.1 117.3 1.0 ND1 B:HIS714 4.2 88.1 1.0 CG B:HIS714 4.2 88.8 1.0 ND1 B:HIS712 4.2 117.8 1.0 O B:ARG729 4.7 111.5 1.0 NH1 B:ARG769 4.8 90.3 1.0 CA B:CYS728 4.8 105.7 1.0 CD2 B:LEU839 4.9 101.6 1.0 CA B:CYS847 4.9 119.0 1.0 C B:CYS728 5.0 108.3 1.0 N B:ARG729 5.0 108.9 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N- Terminal Domain of STAT2 Ordered. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1002 b:182.9 occ:1.00 OE1 B:GLU438 2.1 115.9 1.0 NE2 B:HIS442 2.3 102.6 1.0 SG B:CYS450 2.6 115.6 1.0 CD B:GLU438 2.6 116.4 1.0 OE2 B:GLU438 2.7 117.7 1.0 CD2 B:HIS442 3.0 102.8 1.0 CE1 B:HIS442 3.1 101.1 1.0 CB B:CYS447 3.7 112.1 1.0 SG B:CYS447 3.9 112.1 1.0 CG B:GLU438 3.9 115.3 1.0 CA B:CYS447 3.9 112.8 1.0 N B:GLU448 4.0 132.2 1.0 CG B:HIS442 4.0 100.7 1.0 ND1 B:HIS442 4.0 99.9 1.0 CB B:CYS450 4.0 114.6 1.0 N B:THR449 4.3 106.4 1.0 C B:CYS447 4.5 113.7 1.0 CB B:GLU438 4.5 114.7 1.0 OG1 B:THR449 4.6 106.5 1.0 N B:CYS450 4.6 113.2 1.0 C B:THR449 4.7 105.3 1.0 O B:GLU438 4.8 113.8 1.0 CA B:CYS450 4.9 113.3 1.0 CD1 B:LEU484 4.9 92.6 1.0 O B:LYS446 5.0 114.2 1.0

M.Biswal, J.Lu, J.Song. Cryo-Em Structure of DENV2 NS5 in Complex with Human STAT2 with the N-Terminal Domain of STAT2 Ordered. To Be Published.