Zinc in PDB 7xa4: Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn

All present enzymatic activity of Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn:
1.16.3.2;

The structure of Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn, PDB code: 7xa4 was solved by Y.Liu, G.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.19 / 1.96
Space group	P 32 1 2
Cell size a, b, c (Å), α, β, γ (°)	55.84, 55.84, 129.392, 90, 90, 120
R / Rfree (%)	21.1 / 23.6

The binding sites of Zinc atom in the Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn (pdb code 7xa4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn, PDB code: 7xa4:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:38.7 occ:0.81 OE1 A:GLU19 2.1 33.2 1.0 OE1 A:GLU52 2.2 27.4 1.0 CD2 A:HIS55 2.3 30.3 1.0 O A:HOH303 2.4 38.3 1.0 CD A:GLU19 3.1 40.6 1.0 ZN A:ZN202 3.2 43.1 0.8 CG A:HIS55 3.2 33.2 1.0 CD A:GLU52 3.2 35.9 1.0 NE2 A:HIS55 3.3 36.7 1.0 OE2 A:GLU19 3.4 39.0 1.0 OE2 A:GLU52 3.6 37.3 1.0 CB A:HIS55 3.6 26.7 1.0 OE1 A:GLN129 3.8 41.4 1.0 ND1 A:HIS55 4.4 36.1 1.0 CE1 A:HIS55 4.4 32.7 1.0 CG A:GLU19 4.4 39.7 1.0 OE1 A:GLU132 4.5 55.0 1.0 CG A:GLU52 4.6 23.8 1.0 OE2 A:GLU132 4.6 45.4 1.0 CA A:GLU52 4.6 27.4 1.0 CB A:GLU52 4.8 23.1 1.0 CB A:GLU19 4.8 29.4 1.0 CG1 A:VAL99 4.8 25.1 1.0 CD A:GLU132 4.9 58.0 1.0 CD A:GLN129 5.0 38.0 1.0

Zinc binding site 2 out of 2 in the Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Thermotoga Maritima Ferritin Variant-Tm-E (S111H) with Zn within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:43.1 occ:0.77 OE2 A:GLU52 2.1 37.3 1.0 OE2 A:GLU132 2.1 45.4 1.0 OE2 A:GLU96 2.2 47.7 1.0 OE1 A:GLU96 2.7 39.2 1.0 CD A:GLU96 2.8 45.7 1.0 CD A:GLU52 2.9 35.9 1.0 OE1 A:GLU52 3.0 27.4 1.0 CD A:GLU132 3.2 58.0 1.0 ZN A:ZN201 3.2 38.7 0.8 OE1 A:GLU132 3.5 55.0 1.0 OE1 A:GLN129 3.5 41.4 1.0 NE2 A:GLN48 4.1 32.5 1.0 CG A:GLU96 4.2 36.3 1.0 CG A:GLU52 4.3 23.8 1.0 OH A:TYR26 4.3 44.7 1.0 CE2 A:TYR26 4.4 31.2 1.0 CD A:GLN129 4.4 38.0 1.0 NE2 A:GLN129 4.5 34.5 1.0 CD2 A:HIS55 4.5 30.3 1.0 CG A:GLU132 4.5 44.9 1.0 NE2 A:HIS55 4.8 36.7 1.0 O A:HOH303 4.8 38.3 1.0 CB A:GLU132 4.8 34.1 1.0 OE1 A:GLU19 4.8 33.2 1.0 CZ A:TYR26 4.9 43.9 1.0

Y.Liu, X.Chen, S.Yin, X.Chang, C.Lv, J.Zang, X.Leng, T.Zhang, G.Zhao. Directed Self-Assembly of Dimeric Building Blocks Into Networklike Protein Origami to Construct Hydrogels. Acs Nano V. 16 19472 2022.
ISSN: ESSN 1936-086X
PubMed: 36315654
DOI: 10.1021/ACSNANO.2C09391