Zinc in PDB 7x3p: Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9

The structure of Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9, PDB code: 7x3p was solved by G.-B.Li, J.Deng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.78 / 1.56
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	41.332, 65.034, 55.658, 90, 93.58, 90
R / Rfree (%)	13.9 / 16.3

The structure of Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9 also contains other interesting chemical elements:

Fluorine

(F)

3 atoms

The binding sites of Zinc atom in the Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9 (pdb code 7x3p). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9, PDB code: 7x3p:

Zinc binding site 1 out of 1 in the Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn403 b:10.2 occ:1.00 SG A:CYS212 2.3 9.9 1.0 SG A:CYS207 2.3 9.8 1.0 SG A:CYS166 2.3 9.4 1.0 SG A:CYS169 2.4 11.4 1.0 CB A:CYS207 3.0 9.8 1.0 CB A:CYS166 3.1 9.4 1.0 CB A:CYS212 3.3 12.2 1.0 CB A:CYS169 3.3 10.1 1.0 N A:CYS169 3.8 9.8 1.0 CA A:CYS169 4.1 11.7 1.0 N A:GLY214 4.4 11.4 1.0 CA A:CYS207 4.5 6.8 1.0 CA A:CYS166 4.6 11.0 1.0 CG A:GLU209 4.6 12.6 1.0 CA A:CYS212 4.6 12.4 1.0 CB A:SER168 4.7 10.7 1.0 CB A:GLU209 4.7 11.8 1.0 N A:GLY213 4.7 12.8 1.0 CA A:GLY214 4.8 9.8 1.0 O A:HOH846 4.8 14.3 1.0 C A:CYS169 4.9 10.5 1.0 C A:SER168 4.9 12.8 1.0 C A:CYS212 5.0 13.2 1.0

G.-B.Li, J.Deng. Crystal Structure of Human SIRT5 in Complex with Diazirine Inhibitor 9 To Be Published.