Zinc in PDB 7uo7: Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State

All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State:
2.7.7.48;

The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State (pdb code 7uo7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State, PDB code: 7uo7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1003 b:63.6 occ:1.00 ND1 A:HIS295 2.1 47.1 1.0 SG A:CYS310 2.3 46.6 1.0 SG A:CYS306 2.3 49.4 1.0 SG A:CYS301 2.3 48.5 1.0 CE1 A:HIS295 2.7 47.1 1.0 CG A:HIS295 3.1 47.1 1.0 CB A:CYS301 3.4 48.5 1.0 CA A:CYS301 3.6 48.5 1.0 CB A:HIS295 3.7 47.1 1.0 O A:CYS306 3.7 49.4 1.0 CB A:CYS306 3.7 49.4 1.0 NE2 A:HIS295 3.8 47.1 1.0 CB A:CYS310 3.9 46.6 1.0 CD2 A:HIS295 3.9 47.1 1.0 C A:CYS306 4.1 49.4 1.0 O A:THR293 4.1 49.8 1.0 N A:HIS295 4.2 47.1 1.0 CA A:CYS306 4.4 49.4 1.0 N A:LEU302 4.5 48.9 1.0 ND1 A:HIS309 4.5 47.6 1.0 N A:CYS301 4.5 48.5 1.0 CA A:HIS295 4.5 47.1 1.0 C A:CYS301 4.6 48.5 1.0 N A:ILE307 4.9 47.5 1.0 N A:CYS310 4.9 46.6 1.0

Zinc binding site 2 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1004 b:69.2 occ:1.00 ND1 A:HIS642 1.9 52.6 1.0 SG A:CYS487 2.3 55.1 1.0 SG A:CYS646 2.3 54.0 1.0 SG A:CYS645 2.3 57.3 1.0 CG A:HIS642 2.5 52.6 1.0 CB A:HIS642 2.5 52.6 1.0 CE1 A:HIS642 3.2 52.6 1.0 CB A:CYS646 3.2 54.0 1.0 CA A:HIS642 3.5 52.6 1.0 N A:CYS646 3.7 54.0 1.0 CB A:CYS487 3.8 55.1 1.0 CD2 A:HIS642 3.8 52.6 1.0 CB A:CYS645 3.8 57.3 1.0 O A:HIS642 4.0 52.6 1.0 CA A:CYS646 4.0 54.0 1.0 NE2 A:HIS642 4.1 52.6 1.0 N A:CYS487 4.1 55.1 1.0 C A:CYS645 4.2 57.3 1.0 CE1 A:PHE571 4.3 50.4 1.0 C A:HIS642 4.3 52.6 1.0 CA A:CYS645 4.5 57.3 1.0 CA A:CYS487 4.5 55.1 1.0 N A:HIS642 4.7 52.6 1.0 C A:GLY486 4.7 52.8 1.0 O A:CYS645 4.8 57.3 1.0 CD1 A:PHE571 4.8 50.4 1.0 N A:CYS645 4.9 57.3 1.0 CA A:GLY486 4.9 52.8 1.0 CZ A:PHE571 5.0 50.4 1.0

B.F.Malone, S.A.Darst. Sars-Cov-2 Replication-Transcription Complex Bound to Atp, in A Pre-Catalytic State To Be Published.