Zinc in PDB 7t91: Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region

The structure of Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region, PDB code: 7t91 was solved by M.Wu, S.Zhang, C.E.Augelli-Szanfran, R.J.Boohaker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.79 / 2.05
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	66.728, 66.728, 65.909, 90, 90, 120
R / Rfree (%)	19.2 / 23.6

The binding sites of Zinc atom in the Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region (pdb code 7t91). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region, PDB code: 7t91:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:39.6 occ:1.00 NE2 A:HIS255 2.0 37.1 1.0 NE2 A:HIS260 2.1 43.9 1.0 SG A:CYS237 2.2 39.8 1.0 SG A:CYS242 2.3 43.6 1.0 CD2 A:HIS255 2.9 38.8 1.0 CD2 A:HIS260 2.9 45.0 1.0 CE1 A:HIS255 3.1 41.7 1.0 CB A:CYS237 3.1 43.5 1.0 CB A:CYS242 3.1 49.4 1.0 CE1 A:HIS260 3.2 45.3 1.0 CG A:HIS255 4.1 39.8 1.0 CB A:TRP239 4.1 42.6 1.0 CG A:HIS260 4.1 44.8 1.0 ND1 A:HIS255 4.1 39.8 1.0 ND1 A:HIS260 4.2 42.2 1.0 CA A:CYS237 4.5 43.9 1.0 CA A:CYS242 4.6 53.1 1.0 CB A:GLN244 4.7 60.0 1.0 CG A:GLN244 4.8 60.3 1.0 N A:TRP239 4.9 45.7 1.0 C A:CYS242 5.0 54.5 1.0 CG A:TRP239 5.0 42.1 1.0 C A:CYS237 5.0 43.8 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:39.8 occ:1.00 NE2 A:HIS295 2.0 41.8 1.0 NE2 A:HIS291 2.1 38.4 1.0 SG A:CYS270 2.3 38.2 1.0 SG A:CYS275 2.3 45.0 1.0 CD2 A:HIS295 2.9 42.3 1.0 CD2 A:HIS291 3.0 40.1 1.0 CE1 A:HIS295 3.1 42.4 1.0 CB A:CYS270 3.2 38.2 1.0 CB A:CYS275 3.2 45.7 1.0 CE1 A:HIS291 3.2 36.0 1.0 CB A:TRP272 4.1 41.3 1.0 CG A:HIS295 4.1 40.5 1.0 ND1 A:HIS295 4.2 44.9 1.0 CG A:HIS291 4.2 37.8 1.0 ND1 A:HIS291 4.3 35.8 1.0 CA A:CYS275 4.4 47.9 1.0 O A:HOH509 4.4 45.8 1.0 CA A:CYS270 4.6 37.2 1.0 CG A:ARG277 4.6 58.1 1.0 CE A:MET292 4.6 30.7 1.0 O A:CYS270 4.8 36.5 1.0 CG A:TRP272 4.9 39.4 1.0 C A:CYS270 4.9 39.4 1.0 O A:HOH519 4.9 62.5 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:39.0 occ:1.00 NE2 B:HIS255 2.0 34.5 1.0 NE2 B:HIS260 2.1 47.1 1.0 SG B:CYS237 2.2 42.6 1.0 SG B:CYS242 2.4 41.5 1.0 CD2 B:HIS260 2.9 43.8 1.0 CD2 B:HIS255 3.0 36.2 1.0 CE1 B:HIS255 3.0 36.2 1.0 CB B:CYS237 3.1 47.3 1.0 CB B:CYS242 3.1 43.4 1.0 CE1 B:HIS260 3.2 47.6 1.0 ND1 B:HIS255 4.1 34.6 1.0 CG B:HIS255 4.1 34.0 1.0 CG B:HIS260 4.1 43.2 1.0 CB B:TRP239 4.2 43.7 1.0 ND1 B:HIS260 4.3 42.3 1.0 CA B:CYS237 4.5 48.4 1.0 CB B:GLN244 4.5 54.4 1.0 CA B:CYS242 4.6 48.4 1.0 CG B:GLN244 4.7 58.3 1.0 C B:CYS237 5.0 48.5 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn402 b:40.3 occ:1.00 NE2 B:HIS295 2.0 39.6 1.0 NE2 B:HIS291 2.0 39.3 1.0 SG B:CYS270 2.3 37.3 1.0 SG B:CYS275 2.3 45.4 1.0 CE1 B:HIS291 2.9 40.2 1.0 CD2 B:HIS295 3.0 40.2 1.0 CE1 B:HIS295 3.0 43.0 1.0 CD2 B:HIS291 3.0 39.0 1.0 CB B:CYS270 3.1 35.9 1.0 CB B:CYS275 3.2 47.8 1.0 ND1 B:HIS291 4.1 38.8 1.0 ND1 B:HIS295 4.1 42.2 1.0 CB B:TRP272 4.1 42.7 1.0 CG B:HIS295 4.1 40.2 1.0 CG B:HIS291 4.1 39.7 1.0 O B:HOH511 4.3 46.1 1.0 CA B:CYS275 4.4 50.0 1.0 CA B:CYS270 4.6 38.1 1.0 CD B:ARG277 4.7 53.9 1.0 O B:CYS270 4.8 40.4 1.0 C B:CYS270 4.9 38.5 1.0 SD B:MET292 4.9 42.7 1.0 CG B:TRP272 4.9 41.7 1.0 CE B:MET292 5.0 52.7 1.0

M.Wu, S.Zhang, C.E.Augelli-Szafran, R.J.Boohaker. Crystal Structure of Zinc Finger Motif 1 and 2 of GLI1 Dna Binding Region To Be Published.