Atomistry » Zinc » PDB 7h4f-7hl5 » 7h4j
Atomistry »
  Zinc »
    PDB 7h4f-7hl5 »
      7h4j »

Zinc in PDB 7h4j: Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875)

Enzymatic activity of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875)

All present enzymatic activity of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875):
3.4.22.29;

Protein crystallography data

The structure of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875), PDB code: 7h4j was solved by R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, D.Fearon, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.67 / 1.79
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 72.729, 60.911, 32.396, 90, 93.07, 90
R / Rfree (%) 22 / 24.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875) (pdb code 7h4j). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875), PDB code: 7h4j:

Zinc binding site 1 out of 1 in 7h4j

Go back to Zinc Binding Sites List in 7h4j
Zinc binding site 1 out of 1 in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z53825020 (A71EV2A-X0875) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn203

b:22.5
occ:1.00
 ND1 A:HIS118 2.2 25.4 0.5
SG A:CYS58 2.2 21.5 1.0
SG A:CYS56 2.3 22.2 1.0
SG A:CYS116 2.3 24.8 0.5
CE1 A:HIS118 3.1 25.8 0.5
CB A:CYS58 3.1 21.5 1.0
CB A:CYS56 3.1 21.7 1.0
CG A:HIS118 3.3 25.8 0.5
CB A:CYS116 3.3 24.2 0.5
CB A:HIS118 3.6 24.8 0.5
N A:CYS58 4.2 22.9 1.0
CA A:CYS58 4.2 22.6 1.0
N A:HIS118 4.2 25.1 0.5
NE2 A:HIS118 4.3 26.0 0.5
CD2 A:HIS118 4.4 26.3 0.5
CB A:ALA54 4.4 22.9 1.0
CA A:HIS118 4.5 24.6 0.5
CA A:CYS56 4.6 20.1 1.0
OE1 A:GLN117 4.6 36.8 0.5
CD A:GLN117 4.6 33.9 0.5
CA A:CYS116 4.7 23.9 0.5
CG A:GLN117 4.7 31.9 0.5
N A:GLN117 4.8 28.5 0.5
C A:CYS116 4.9 25.1 0.5
NH1 A:ARG138 4.9 20.5 1.0

Reference:

R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, D.Fearon, F.Von Delft. Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease To Be Published.
Page generated: Fri Aug 22 00:41:54 2025

Last articles

Zn in 7W4Y
Zn in 7W4X
Zn in 7W4Q
Zn in 7W4N
Zn in 7W4M
Zn in 7W4L
Zn in 7W4K
Zn in 7W4J
Zn in 7W4G
Zn in 7W4F
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy