Zinc in PDB 7ej3: Utp Cyclohydrolase

The structure of Utp Cyclohydrolase, PDB code: 7ej3 was solved by H.Zhang, Y.Zhang, Z.Yuchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.93 / 1.60
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	115.152, 115.152, 283.489, 90, 90, 120
R / Rfree (%)	13.9 / 17.3

The binding sites of Zinc atom in the Utp Cyclohydrolase (pdb code 7ej3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Utp Cyclohydrolase, PDB code: 7ej3:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Utp Cyclohydrolase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Utp Cyclohydrolase within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:13.3 occ:0.82 O A:HOH1334 2.2 17.1 1.0 SG A:CYS265 2.3 16.4 1.0 SG A:CYS267 2.3 16.5 1.0 SG A:CYS254 2.3 16.1 1.0 CB A:CYS254 3.2 12.8 1.0 CB A:CYS265 3.2 14.8 1.0 CB A:CYS267 3.2 14.2 1.0 CB A:SER257 3.9 14.0 1.0 O A:HOH1088 4.0 18.4 1.0 NZ A:LYS305 4.2 17.0 1.0 N A:CYS267 4.3 15.0 1.0 CA A:CYS267 4.4 14.8 1.0 CA A:CYS265 4.6 14.4 1.0 CA A:CYS254 4.6 11.4 1.0 OG A:SER257 4.6 14.9 1.0 CE A:LYS305 4.7 19.8 1.0 C A:CYS265 4.9 16.8 1.0 N A:THR266 4.9 16.9 1.0 OH A:TYR309 4.9 16.6 1.0

Zinc binding site 2 out of 2 in the Utp Cyclohydrolase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Utp Cyclohydrolase within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:12.1 occ:0.83 SG B:CYS265 2.3 15.5 1.0 SG B:CYS254 2.3 14.5 1.0 SG B:CYS267 2.3 14.5 1.0 CB B:CYS254 3.2 11.3 1.0 CB B:CYS265 3.2 14.0 1.0 CB B:CYS267 3.2 12.0 1.0 CB B:SER257 3.9 12.0 1.0 O B:HOH848 4.0 16.9 1.0 NZ B:LYS305 4.2 18.2 1.0 N B:CYS267 4.3 12.5 1.0 CA B:CYS267 4.4 12.9 1.0 CA B:CYS265 4.6 13.9 1.0 OG B:SER257 4.6 13.5 1.0 CA B:CYS254 4.6 12.7 1.0 CE B:LYS305 4.8 18.3 1.0 C B:CYS265 4.8 13.1 1.0 N B:THR266 4.9 14.7 1.0 OH B:TYR309 4.9 16.5 1.0

H.Zhang, Y.Wei, L.Lin, J.Liu, R.Chu, P.Cao, E.L.Ang, H.Zhao, Z.Yuchi, Y.Zhang. Structural and Biochemical Investigation of Utp Cyclohydrolase Acs Catalysis 8895 2021.
ISSN: ESSN 2155-5435
DOI: 10.1021/ACSCATAL.1C02252