Zinc in PDB 7e7e: The Co-Crystal Structure of ACE2 with Fab

The structure of The Co-Crystal Structure of ACE2 with Fab, PDB code: 7e7e was solved by J.Y.Xiao, Y.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.84 / 3.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	98.779, 115.462, 224.668, 90, 90, 90
R / Rfree (%)	27.6 / 32.7

The binding sites of Zinc atom in the The Co-Crystal Structure of ACE2 with Fab (pdb code 7e7e). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Co-Crystal Structure of ACE2 with Fab, PDB code: 7e7e:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Co-Crystal Structure of ACE2 with Fab


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Co-Crystal Structure of ACE2 with Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:105.0 occ:1.00 OE1 A:GLU402 2.1 98.7 1.0 NE2 A:HIS374 2.3 120.1 1.0 NE2 A:HIS378 2.3 106.2 1.0 OE2 A:GLU402 2.6 97.5 1.0 CD A:GLU402 2.7 97.2 1.0 CE1 A:HIS378 3.0 98.3 1.0 CD2 A:HIS374 3.2 114.8 1.0 CE1 A:HIS374 3.4 119.7 1.0 CD2 A:HIS378 3.5 99.8 1.0 OE2 A:GLU375 3.6 90.6 1.0 CG A:GLU402 4.2 93.7 1.0 ND1 A:HIS378 4.3 92.0 1.0 CG A:HIS374 4.4 113.4 1.0 OH A:TYR515 4.4 90.3 1.0 ND1 A:HIS374 4.4 119.2 1.0 CG A:HIS378 4.5 92.5 1.0 CD A:GLU375 4.7 91.1 1.0 CB A:GLU402 4.8 92.5 1.0 CE1 A:TYR515 4.9 93.9 1.0 CA A:GLU402 4.9 100.2 1.0

Zinc binding site 2 out of 2 in the The Co-Crystal Structure of ACE2 with Fab


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Co-Crystal Structure of ACE2 with Fab within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:191.8 occ:1.00 OE2 B:GLU402 2.1 153.0 1.0 NE2 B:HIS374 2.3 112.1 1.0 NE2 B:HIS378 2.3 114.1 1.0 CD B:GLU402 2.8 137.9 1.0 OE1 B:GLU402 2.9 135.2 1.0 CD2 B:HIS374 3.1 106.7 1.0 OE2 B:GLU375 3.2 102.8 1.0 CD2 B:HIS378 3.3 107.7 1.0 CE1 B:HIS378 3.3 111.2 1.0 CE1 B:HIS374 3.4 108.5 1.0 CG B:GLU402 4.2 127.7 1.0 CD B:GLU375 4.3 98.0 1.0 CG B:HIS374 4.3 103.8 1.0 ND1 B:HIS378 4.4 105.5 1.0 CG B:HIS378 4.4 102.6 1.0 ND1 B:HIS374 4.4 104.2 1.0 OE1 B:GLU375 4.7 98.6 1.0 CB B:GLU402 5.0 122.0 1.0 CA B:GLU402 5.0 119.9 1.0

J.Y.Xiao, Y.Zhang. The Co-Crystal Structure of ACE2 with Fab To Be Published.