Atomistry » Zinc » PDB 7crq-7d4q » 7cxn
Atomistry »
  Zinc »
    PDB 7crq-7d4q »
      7cxn »

Zinc in PDB 7cxn: Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex

Enzymatic activity of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex

All present enzymatic activity of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex:
2.7.7.48; 3.4.19.12; 3.4.22.69; 3.6.4.12; 3.6.4.13;

Zinc Binding Sites:

The binding sites of Zinc atom in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex (pdb code 7cxn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex, PDB code: 7cxn:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 1 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1001

b:0.1
occ:1.00
 ND1 A:HIS295 2.0 0.1 1.0
SG A:CYS301 2.3 0.8 1.0
SG A:CYS306 2.3 0.0 1.0
SG A:CYS310 2.3 0.1 1.0
CE1 A:HIS295 2.5 0.1 1.0
CG A:HIS295 3.0 0.1 1.0
O A:CYS306 3.2 0.0 1.0
CB A:CYS301 3.4 0.8 1.0
CB A:CYS306 3.5 0.0 1.0
NE2 A:HIS295 3.5 0.1 1.0
CB A:CYS310 3.6 0.1 1.0
C A:CYS306 3.6 0.0 1.0
CA A:CYS301 3.6 0.8 1.0
CB A:HIS295 3.8 0.1 1.0
CD2 A:HIS295 3.8 0.1 1.0
CA A:CYS306 4.0 0.0 1.0
N A:ILE307 4.4 0.5 1.0
N A:CYS301 4.5 0.8 1.0
O A:ASN300 4.5 0.4 1.0
N A:HIS295 4.6 0.1 1.0
CA A:HIS295 4.8 0.1 1.0
C A:ASN300 4.8 0.4 1.0
CA A:CYS310 4.8 0.1 1.0
CA A:ILE307 4.8 0.5 1.0
N A:CYS310 4.8 0.1 1.0
C A:CYS301 4.9 0.8 1.0
N A:LEU302 4.9 0.0 1.0

Zinc binding site 2 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 2 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1002

b:0.0
occ:1.00
 ND1 A:HIS642 2.0 0.6 1.0
CE1 A:HIS642 2.2 0.6 1.0
SG A:CYS487 2.3 0.8 1.0
SG A:CYS646 2.3 0.5 1.0
SG A:CYS645 2.3 0.1 1.0
CG A:HIS642 3.1 0.6 1.0
O A:CYS645 3.1 0.1 1.0
NE2 A:HIS642 3.3 0.6 1.0
CE1 A:PHE571 3.3 0.7 1.0
CB A:CYS645 3.5 0.1 1.0
C A:CYS645 3.5 0.1 1.0
CB A:CYS487 3.6 0.8 1.0
N A:CYS487 3.7 0.8 1.0
CD2 A:HIS642 3.7 0.6 1.0
CB A:CYS646 3.8 0.5 1.0
CD1 A:PHE571 3.9 0.7 1.0
NZ A:LYS532 3.9 0.0 1.0
CB A:HIS642 4.0 0.6 1.0
N A:CYS646 4.0 0.5 1.0
CA A:CYS487 4.0 0.8 1.0
CA A:CYS645 4.1 0.1 1.0
CE A:LYS532 4.3 0.0 1.0
CZ A:PHE571 4.3 0.7 1.0
CA A:CYS646 4.4 0.5 1.0
C A:GLY486 4.6 0.6 1.0
CA A:GLY486 4.9 0.6 1.0
N A:CYS645 4.9 0.1 1.0
CA A:HIS642 5.0 0.6 1.0

Zinc binding site 3 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 3 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn1000

b:0.1
occ:1.00
 SG F:CYS26 2.3 0.1 1.0
SG F:CYS8 2.3 0.8 1.0
SG F:CYS29 2.3 0.0 1.0
SG F:CYS5 2.3 0.0 1.0
CB F:CYS26 2.4 0.1 1.0
CB F:CYS29 2.9 0.0 1.0
CB F:CYS8 3.1 0.8 1.0
CB F:CYS5 3.2 0.0 1.0
N F:CYS26 3.4 0.1 1.0
CA F:CYS26 3.5 0.1 1.0
N F:CYS8 3.5 0.8 1.0
CA F:GLY99 3.8 0.1 1.0
CA F:CYS8 3.8 0.8 1.0
N F:CYS29 4.1 0.0 1.0
CA F:CYS29 4.1 0.0 1.0
N F:GLY99 4.2 0.1 1.0
C F:CYS26 4.3 0.1 1.0
C F:CYS8 4.5 0.8 1.0
CB F:LEU7 4.5 0.4 1.0
C F:LEU7 4.6 0.4 1.0
C F:GLY99 4.6 0.1 1.0
O F:CYS26 4.6 0.1 1.0
CA F:CYS5 4.7 0.0 1.0
C F:LEU25 4.7 0.7 1.0
N F:ASN9 4.8 0.8 1.0
N F:SER100 4.9 0.5 1.0
OG F:SER10 4.9 0.2 1.0
N F:LEU7 4.9 0.4 1.0
CA F:LEU7 4.9 0.4 1.0

Zinc binding site 4 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 4 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn1001

b:0.7
occ:1.00
 ND1 F:HIS75 2.0 0.2 1.0
SG F:CYS55 2.3 0.7 1.0
SG F:CYS72 2.3 0.4 1.0
SG F:CYS50 2.3 0.9 1.0
CG F:HIS75 2.4 0.2 1.0
CE1 F:HIS75 2.7 0.2 1.0
CB F:CYS72 2.7 0.4 1.0
CB F:CYS55 2.7 0.7 1.0
CB F:HIS75 3.0 0.2 1.0
CD2 F:HIS75 3.1 0.2 1.0
NE2 F:HIS75 3.2 0.2 1.0
CB F:CYS50 3.5 0.9 1.0
N F:CYS72 3.6 0.4 1.0
CA F:CYS72 3.7 0.4 1.0
OG F:SER74 4.0 0.8 1.0
N F:HIS75 4.1 0.2 1.0
CA F:HIS75 4.2 0.2 1.0
CA F:CYS55 4.2 0.7 1.0
CB F:ALA52 4.3 0.9 1.0
C F:CYS72 4.5 0.4 1.0
CG2 F:VAL57 4.5 1.0 1.0
O F:CYS55 4.7 0.7 1.0
O F:CYS72 4.8 0.4 1.0
O F:ALA52 4.8 0.9 1.0
C F:CYS55 4.8 0.7 1.0
CA F:CYS50 4.9 0.9 1.0
C F:TYR71 4.9 0.8 1.0

Zinc binding site 5 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 5 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn1002

b:0.8
occ:1.00
 CE1 F:HIS33 1.3 0.2 1.0
ND1 F:HIS39 2.0 0.7 1.0
ND1 F:HIS33 2.1 0.2 1.0
SG F:CYS16 2.3 0.8 1.0
SG F:CYS19 2.3 0.4 1.0
NE2 F:HIS33 2.5 0.2 1.0
CE1 F:HIS39 2.8 0.7 1.0
CB F:CYS16 3.1 0.8 1.0
CG F:HIS39 3.2 0.7 1.0
CG F:HIS33 3.3 0.2 1.0
CB F:CYS19 3.4 0.4 1.0
CD2 F:HIS33 3.5 0.2 1.0
CB F:HIS39 3.7 0.7 1.0
NE2 F:HIS39 4.0 0.7 1.0
N F:CYS19 4.1 0.4 1.0
CD2 F:HIS39 4.2 0.7 1.0
CA F:CYS19 4.2 0.4 1.0
CB F:ALA110 4.5 0.8 1.0
CA F:CYS16 4.5 0.8 1.0
O F:CYS16 4.6 0.8 1.0
CB F:HIS33 4.6 0.2 1.0
CD1 F:LEU25 4.7 0.7 1.0
CE2 F:PHE106 4.7 0.8 1.0
CZ F:PHE106 4.8 0.8 1.0
C F:CYS16 4.9 0.8 1.0
C F:ALA18 5.0 0.9 1.0

Zinc binding site 6 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 6 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn701

b:0.4
occ:1.00
 SG E:CYS29 2.3 0.3 1.0
SG E:CYS26 2.3 0.4 1.0
SG E:CYS5 2.3 0.7 1.0
SG E:CYS8 2.3 0.1 1.0
CB E:CYS26 2.8 0.4 1.0
CB E:CYS29 3.2 0.3 1.0
CB E:CYS8 3.4 0.1 1.0
CB E:CYS5 3.6 0.7 1.0
N E:CYS8 3.7 0.1 1.0
N E:CYS26 3.8 0.4 1.0
CA E:CYS26 3.8 0.4 1.0
CB E:LEU7 3.9 0.8 1.0
CA E:GLY99 4.0 0.3 1.0
CA E:CYS8 4.2 0.1 1.0
C E:LEU7 4.3 0.8 1.0
N E:CYS29 4.3 0.3 1.0
CA E:CYS29 4.3 0.3 1.0
N E:GLY99 4.4 0.3 1.0
CA E:LEU7 4.5 0.8 1.0
C E:CYS26 4.6 0.4 1.0
N E:LEU7 4.6 0.8 1.0
N E:SER100 4.7 0.1 1.0
C E:GLY99 4.7 0.3 1.0
CG E:LEU7 4.9 0.8 1.0
O E:CYS26 4.9 0.4 1.0
CA E:CYS5 4.9 0.7 1.0

Zinc binding site 7 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 7 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn702

b:0.8
occ:1.00
 ND1 E:HIS75 2.1 0.7 1.0
CB E:CYS72 2.2 0.6 1.0
SG E:CYS55 2.3 0.7 1.0
SG E:CYS72 2.3 0.6 1.0
SG E:CYS50 2.3 0.3 1.0
CB E:CYS55 2.3 0.7 1.0
CE1 E:HIS75 2.6 0.7 1.0
CG E:HIS75 3.2 0.7 1.0
CB E:CYS50 3.2 0.3 1.0
CA E:CYS72 3.4 0.6 1.0
N E:CYS72 3.5 0.6 1.0
NE2 E:HIS75 3.7 0.7 1.0
CA E:CYS55 3.8 0.7 1.0
CB E:HIS75 3.9 0.7 1.0
CD2 E:HIS75 4.0 0.7 1.0
OG E:SER74 4.4 0.1 1.0
CB E:ALA52 4.4 0.2 1.0
N E:HIS75 4.4 0.7 1.0
C E:CYS72 4.4 0.6 1.0
N E:CYS55 4.6 0.7 1.0
CA E:CYS50 4.6 0.3 1.0
C E:CYS55 4.7 0.7 1.0
O E:ALA52 4.7 0.2 1.0
C E:TYR71 4.7 0.1 1.0
CA E:HIS75 4.8 0.7 1.0
N E:LYS73 4.8 0.0 1.0
O E:CYS55 4.9 0.7 1.0

Zinc binding site 8 out of 8 in 7cxn

Go back to Zinc Binding Sites List in 7cxn
Zinc binding site 8 out of 8 in the Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn703

b:0.6
occ:1.00
 CG E:HIS39 1.9 0.5 1.0
ND1 E:HIS39 2.0 0.5 1.0
NE2 E:HIS33 2.0 0.3 1.0
SG E:CYS16 2.3 0.8 1.0
SG E:CYS19 2.3 0.1 1.0
CB E:HIS39 2.5 0.5 1.0
CD2 E:HIS39 2.5 0.5 1.0
CE1 E:HIS33 2.5 0.3 1.0
CE1 E:HIS39 2.6 0.5 1.0
NE2 E:HIS39 2.9 0.5 1.0
N E:CYS19 2.9 0.1 1.0
CB E:CYS19 3.1 0.1 1.0
CA E:CYS19 3.3 0.1 1.0
CD2 E:HIS33 3.3 0.3 1.0
CB E:CYS16 3.7 0.8 1.0
C E:ALA18 3.8 0.4 1.0
ND1 E:HIS33 3.8 0.3 1.0
CA E:HIS39 3.8 0.5 1.0
CB E:ALA18 4.0 0.4 1.0
CG E:HIS33 4.2 0.3 1.0
O E:CYS16 4.3 0.8 1.0
CA E:ALA18 4.4 0.4 1.0
C E:HIS39 4.5 0.5 1.0
O E:ALA18 4.5 0.4 1.0
O E:HIS39 4.8 0.5 1.0
N E:HIS39 4.8 0.5 1.0
C E:CYS19 4.8 0.1 1.0
N E:ALA18 4.8 0.4 1.0
CA E:CYS16 4.8 0.8 1.0
C E:CYS16 4.9 0.8 1.0

Reference:

L.Yan, Y.Zhang, J.Ge, L.Zheng, Y.Gao, T.Wang, Z.Jia, H.Wang, Y.Huang, M.Li, Q.Wang, Z.Rao, Z.Lou. Architecture of A Sars-Cov-2 Mini Replication and Transcription Complex. Nat Commun V. 11 5874 2020.
ISSN: ESSN 2041-1723
PubMed: 33208736
DOI: 10.1038/S41467-020-19770-1
Page generated: Tue Oct 29 18:29:27 2024

Last articles

Mg in 6HVW
Mg in 6HVV
Mg in 6HVU
Mg in 6HVT
Mg in 6HVS
Mg in 6HVR
Mg in 6HVA
Mg in 6HV7
Mg in 6HV5
Mg in 6HV4
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy