|
Atomistry » Zinc » PDB 7c3s-7ci4 » 7cbj | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 7c3s-7ci4 » 7cbj » |
Zinc in PDB 7cbj: Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36Enzymatic activity of Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36
All present enzymatic activity of Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36:
3.1.4.53; Protein crystallography data
The structure of Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36, PDB code: 7cbj
was solved by
X.L.Zhang,
Y.C.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7cbj:
The structure of Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36
(pdb code 7cbj). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36, PDB code: 7cbj: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 7cbjGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 7cbjGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of PDE4D Catalytic Domain in Complex with Compound 36
![]() Mono view ![]() Stereo pair view
Reference:
R.Zhang,
H.Li,
X.Zhang,
J.Li,
H.Su,
Q.Lu,
G.Dong,
H.Dou,
C.Fan,
Z.Gu,
Q.Mu,
W.Tang,
Y.Xu,
H.Liu.
Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinolines Derivatives As Novel, Selective PDE4 Inhibitors For Antipsoriasis Treatment. Eur.J.Med.Chem. V. 211 13004 2021.
Page generated: Tue Oct 29 18:08:55 2024
ISSN: ISSN 0223-5234 PubMed: 33218684 DOI: 10.1016/J.EJMECH.2020.113004 |
Last articlesMg in 3CC2Mg in 3CCE Mg in 3CC7 Mg in 3CC4 Mg in 3CB3 Mg in 3CC6 Mg in 3C9U Mg in 3CBT Mg in 3CBQ Mg in 3CBG |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |