Zinc in PDB 7bv1: Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex

All present enzymatic activity of Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex:
3.4.19.12; 3.4.22.69;

The binding sites of Zinc atom in the Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex (pdb code 7bv1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex, PDB code: 7bv1:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:38.8 occ:1.00 SG A:CYS310 2.3 20.6 1.0 ND1 A:HIS295 2.3 25.5 1.0 SG A:CYS301 2.4 26.9 1.0 SG A:CYS306 2.4 27.3 1.0 CE1 A:HIS295 3.1 25.5 1.0 CG A:HIS295 3.3 25.5 1.0 CB A:CYS301 3.4 26.9 1.0 O A:CYS306 3.4 27.3 1.0 CB A:CYS310 3.6 20.6 1.0 CB A:CYS306 3.6 27.3 1.0 CB A:HIS295 3.7 25.5 1.0 CA A:CYS301 3.7 26.9 1.0 C A:CYS306 3.8 27.3 1.0 CA A:CYS306 4.1 27.3 1.0 NE2 A:HIS295 4.3 25.5 1.0 N A:HIS295 4.3 25.5 1.0 CD2 A:HIS295 4.4 25.5 1.0 N A:CYS301 4.5 26.9 1.0 N A:ILE307 4.6 23.3 1.0 CA A:HIS295 4.6 25.5 1.0 CA A:CYS310 4.8 20.6 1.0 N A:CYS310 4.8 20.6 1.0 O A:ASN300 4.8 25.3 1.0 O A:HIS295 4.9 25.5 1.0 O A:THR293 4.9 28.7 1.0 N A:LEU302 4.9 28.6 1.0 C A:CYS301 4.9 26.9 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:74.8 occ:1.00 ND1 A:HIS642 2.1 38.0 1.0 SG A:CYS487 2.3 41.4 1.0 SG A:CYS645 2.4 44.4 1.0 SG A:CYS646 2.6 42.6 1.0 CG A:HIS642 2.8 38.0 1.0 CB A:HIS642 2.9 38.0 1.0 CE1 A:HIS642 3.2 38.0 1.0 CB A:CYS645 3.6 44.4 1.0 CB A:CYS646 3.8 42.6 1.0 CA A:HIS642 3.9 38.0 1.0 CB A:CYS487 3.9 41.4 1.0 N A:CYS487 3.9 41.4 1.0 CD2 A:HIS642 4.0 38.0 1.0 CE1 A:PHE571 4.1 31.1 1.0 N A:CYS646 4.1 42.6 1.0 C A:CYS645 4.1 44.4 1.0 NE2 A:HIS642 4.2 38.0 1.0 CA A:CYS645 4.4 44.4 1.0 CA A:CYS487 4.5 41.4 1.0 O A:CYS645 4.6 44.4 1.0 CA A:CYS646 4.6 42.6 1.0 CD1 A:PHE571 4.7 31.1 1.0 C A:HIS642 4.7 38.0 1.0 C A:GLY486 4.7 38.1 1.0 O A:HIS642 4.7 38.0 1.0 CA A:GLY486 4.7 38.1 1.0 CZ A:PHE571 4.8 31.1 1.0 N A:CYS645 4.9 44.4 1.0

W.Yin, C.Mao, X.Luan, D.Shen, Q.Shen, H.Su, X.Wang, F.Zhou, W.Zhao, M.Gao, S.Chang, Y.C.Xie, G.Tian, H.W.Jiang, S.C.Tao, J.Shen, Y.Jiang, H.Jiang, Y.Xu, S.Zhang, Y.Zhang, H.E.Xu. Cryo-Em Structure of the Apo NSP12-NSP7-NSP8 Complex To Be Published.