Atomistry » Zinc » PDB 6yzp-6z89 » 6z85
Atomistry »
  Zinc »
    PDB 6yzp-6z89 »
      6z85 »

Zinc in PDB 6z85: Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex

Enzymatic activity of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex

All present enzymatic activity of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex:
3.5.4.16;

Zinc Binding Sites:

The binding sites of Zinc atom in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex (pdb code 6z85). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex, PDB code: 6z85:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Zinc binding site 1 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 1 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:0.0
occ:1.00
 SG A:CYS141 2.4 0.0 1.0
SG A:CYS212 2.5 0.0 1.0
CB A:CYS212 2.7 0.0 1.0
ND1 A:HIS144 2.9 0.0 1.0
CB A:CYS141 3.3 0.0 1.0
CB A:HIS144 3.5 0.0 1.0
CG A:HIS144 3.5 0.0 1.0
N A:HIS144 3.8 0.0 1.0
CE1 A:HIS144 3.9 0.0 1.0
CA A:CYS212 4.2 0.0 1.0
CB A:HIS143 4.2 0.0 1.0
CA A:HIS144 4.2 0.0 1.0
N A:CYS212 4.7 0.0 1.0
C A:HIS143 4.7 0.0 1.0
CD2 A:HIS144 4.7 0.0 1.0
CA A:CYS141 4.8 0.0 1.0
CA A:HIS143 4.8 0.0 1.0
N A:HIS143 4.8 0.0 1.0
NE2 A:HIS144 4.9 0.0 1.0

Zinc binding site 2 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 2 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn301

b:0.0
occ:1.00
 SG C:CYS141 2.4 0.0 1.0
SG C:CYS212 2.5 0.0 1.0
CB C:CYS212 2.7 0.0 1.0
ND1 C:HIS144 2.9 0.0 1.0
CB C:CYS141 3.3 0.0 1.0
CB C:HIS144 3.5 0.0 1.0
CG C:HIS144 3.5 0.0 1.0
N C:HIS144 3.8 0.0 1.0
CE1 C:HIS144 3.9 0.0 1.0
CA C:CYS212 4.2 0.0 1.0
CB C:HIS143 4.2 0.0 1.0
CA C:HIS144 4.2 0.0 1.0
N C:CYS212 4.7 0.0 1.0
C C:HIS143 4.7 0.0 1.0
CD2 C:HIS144 4.7 0.0 1.0
CA C:CYS141 4.8 0.0 1.0
CA C:HIS143 4.8 0.0 1.0
N C:HIS143 4.8 0.0 1.0
NE2 C:HIS144 4.9 0.0 1.0

Zinc binding site 3 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 3 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn301

b:0.0
occ:1.00
 SG D:CYS141 2.4 0.0 1.0
SG D:CYS212 2.5 0.0 1.0
CB D:CYS212 2.7 0.0 1.0
ND1 D:HIS144 2.9 0.0 1.0
CB D:CYS141 3.3 0.0 1.0
CB D:HIS144 3.5 0.0 1.0
CG D:HIS144 3.5 0.0 1.0
N D:HIS144 3.8 0.0 1.0
CE1 D:HIS144 3.9 0.0 1.0
CA D:CYS212 4.2 0.0 1.0
CB D:HIS143 4.2 0.0 1.0
CA D:HIS144 4.2 0.0 1.0
N D:CYS212 4.7 0.0 1.0
C D:HIS143 4.7 0.0 1.0
CD2 D:HIS144 4.7 0.0 1.0
CA D:CYS141 4.8 0.0 1.0
CA D:HIS143 4.8 0.0 1.0
N D:HIS143 4.8 0.0 1.0
NE2 D:HIS144 4.9 0.0 1.0

Zinc binding site 4 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 4 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn301

b:0.0
occ:1.00
 SG B:CYS141 2.4 0.0 1.0
SG B:CYS212 2.5 0.0 1.0
CB B:CYS212 2.7 0.0 1.0
ND1 B:HIS144 2.9 0.0 1.0
CB B:CYS141 3.3 0.0 1.0
CB B:HIS144 3.5 0.0 1.0
CG B:HIS144 3.5 0.0 1.0
N B:HIS144 3.8 0.0 1.0
CE1 B:HIS144 3.9 0.0 1.0
CA B:CYS212 4.2 0.0 1.0
CB B:HIS143 4.2 0.0 1.0
CA B:HIS144 4.2 0.0 1.0
N B:CYS212 4.7 0.0 1.0
C B:HIS143 4.7 0.0 1.0
CD2 B:HIS144 4.7 0.0 1.0
CA B:CYS141 4.8 0.0 1.0
CA B:HIS143 4.8 0.0 1.0
N B:HIS143 4.8 0.0 1.0
NE2 B:HIS144 4.9 0.0 1.0

Zinc binding site 5 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 5 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn301

b:0.0
occ:1.00
 SG E:CYS141 2.4 0.0 1.0
SG E:CYS212 2.5 0.0 1.0
CB E:CYS212 2.7 0.0 1.0
ND1 E:HIS144 2.9 0.0 1.0
CB E:CYS141 3.3 0.0 1.0
CB E:HIS144 3.5 0.0 1.0
CG E:HIS144 3.5 0.0 1.0
N E:HIS144 3.8 0.0 1.0
CE1 E:HIS144 3.9 0.0 1.0
CA E:CYS212 4.2 0.0 1.0
CB E:HIS143 4.2 0.0 1.0
CA E:HIS144 4.2 0.0 1.0
N E:CYS212 4.7 0.0 1.0
C E:HIS143 4.7 0.0 1.0
CD2 E:HIS144 4.7 0.0 1.0
CA E:CYS141 4.8 0.0 1.0
CA E:HIS143 4.8 0.0 1.0
N E:HIS143 4.8 0.0 1.0
NE2 E:HIS144 4.9 0.0 1.0

Zinc binding site 6 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 6 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Zn301

b:0.0
occ:1.00
 SG G:CYS141 2.4 0.0 1.0
SG G:CYS212 2.5 0.0 1.0
CB G:CYS212 2.7 0.0 1.0
ND1 G:HIS144 2.9 0.0 1.0
CB G:CYS141 3.3 0.0 1.0
CB G:HIS144 3.5 0.0 1.0
CG G:HIS144 3.5 0.0 1.0
N G:HIS144 3.8 0.0 1.0
CE1 G:HIS144 3.9 0.0 1.0
CA G:CYS212 4.2 0.0 1.0
CB G:HIS143 4.2 0.0 1.0
CA G:HIS144 4.2 0.0 1.0
N G:CYS212 4.7 0.0 1.0
C G:HIS143 4.7 0.0 1.0
CD2 G:HIS144 4.7 0.0 1.0
CA G:CYS141 4.8 0.0 1.0
CA G:HIS143 4.8 0.0 1.0
N G:HIS143 4.8 0.0 1.0
NE2 G:HIS144 4.9 0.0 1.0

Zinc binding site 7 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 7 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn301

b:0.0
occ:1.00
 SG H:CYS141 2.4 0.0 1.0
SG H:CYS212 2.5 0.0 1.0
CB H:CYS212 2.7 0.0 1.0
ND1 H:HIS144 2.9 0.0 1.0
CB H:CYS141 3.3 0.0 1.0
CB H:HIS144 3.5 0.0 1.0
CG H:HIS144 3.5 0.0 1.0
N H:HIS144 3.8 0.0 1.0
CE1 H:HIS144 3.9 0.0 1.0
CA H:CYS212 4.2 0.0 1.0
CB H:HIS143 4.2 0.0 1.0
CA H:HIS144 4.2 0.0 1.0
N H:CYS212 4.7 0.0 1.0
C H:HIS143 4.7 0.0 1.0
CD2 H:HIS144 4.7 0.0 1.0
CA H:CYS141 4.8 0.0 1.0
CA H:HIS143 4.8 0.0 1.0
N H:HIS143 4.8 0.0 1.0
NE2 H:HIS144 4.9 0.0 1.0

Zinc binding site 8 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 8 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn301

b:0.0
occ:1.00
 SG I:CYS141 2.4 0.0 1.0
SG I:CYS212 2.5 0.0 1.0
CB I:CYS212 2.7 0.0 1.0
ND1 I:HIS144 2.9 0.0 1.0
CB I:CYS141 3.3 0.0 1.0
CB I:HIS144 3.5 0.0 1.0
CG I:HIS144 3.5 0.0 1.0
N I:HIS144 3.8 0.0 1.0
CE1 I:HIS144 3.9 0.0 1.0
CA I:CYS212 4.2 0.0 1.0
CB I:HIS143 4.2 0.0 1.0
CA I:HIS144 4.2 0.0 1.0
N I:CYS212 4.7 0.0 1.0
C I:HIS143 4.7 0.0 1.0
CD2 I:HIS144 4.7 0.0 1.0
CA I:CYS141 4.8 0.0 1.0
CA I:HIS143 4.8 0.0 1.0
N I:HIS143 4.8 0.0 1.0
NE2 I:HIS144 4.9 0.0 1.0

Zinc binding site 9 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 9 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn301

b:0.0
occ:1.00
 SG J:CYS141 2.4 0.0 1.0
SG J:CYS212 2.5 0.0 1.0
CB J:CYS212 2.7 0.0 1.0
ND1 J:HIS144 2.9 0.0 1.0
CB J:CYS141 3.3 0.0 1.0
CB J:HIS144 3.5 0.0 1.0
CG J:HIS144 3.5 0.0 1.0
N J:HIS144 3.8 0.0 1.0
CE1 J:HIS144 3.9 0.0 1.0
CA J:CYS212 4.2 0.0 1.0
CB J:HIS143 4.2 0.0 1.0
CA J:HIS144 4.2 0.0 1.0
N J:CYS212 4.7 0.0 1.0
C J:HIS143 4.7 0.0 1.0
CD2 J:HIS144 4.7 0.0 1.0
CA J:CYS141 4.8 0.0 1.0
CA J:HIS143 4.8 0.0 1.0
N J:HIS143 4.8 0.0 1.0
NE2 J:HIS144 4.9 0.0 1.0

Zinc binding site 10 out of 10 in 6z85

Go back to Zinc Binding Sites List in 6z85
Zinc binding site 10 out of 10 in the Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 10 of Inhibitory Human Gtp Cyclohydrolase I - Gfrp Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn301

b:0.0
occ:1.00
 SG F:CYS141 2.4 0.0 1.0
SG F:CYS212 2.5 0.0 1.0
CB F:CYS212 2.7 0.0 1.0
ND1 F:HIS144 2.9 0.0 1.0
CB F:CYS141 3.3 0.0 1.0
CB F:HIS144 3.5 0.0 1.0
CG F:HIS144 3.5 0.0 1.0
N F:HIS144 3.8 0.0 1.0
CE1 F:HIS144 3.9 0.0 1.0
CA F:CYS212 4.2 0.0 1.0
CB F:HIS143 4.2 0.0 1.0
CA F:HIS144 4.2 0.0 1.0
N F:CYS212 4.7 0.0 1.0
C F:HIS143 4.7 0.0 1.0
CD2 F:HIS144 4.7 0.0 1.0
CA F:CYS141 4.8 0.0 1.0
CA F:HIS143 4.8 0.0 1.0
N F:HIS143 4.8 0.0 1.0
NE2 F:HIS144 4.9 0.0 1.0

Reference:

R.Ebenhoch, S.Prinz, S.Kaltwasser, D.J.Mills, R.Meinecke, M.Rubbelke, D.Reinert, M.Bauer, L.Weixler, M.Zeeb, J.Vonck, H.Nar. A Hybrid Approach Reveals the Allosteric Regulation of Gtp Cyclohydrolase I. Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
PubMed: 33229582
DOI: 10.1073/PNAS.2013473117
Page generated: Tue Oct 29 15:30:48 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy