Zinc in PDB 6slm: Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP

All present enzymatic activity of Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP:
2.3.2.26;

The structure of Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP, PDB code: 6slm was solved by M.Conrady, G.Gogl, A.Cousido-Siah, A.Mitschler, G.Trave, C.Simon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.21 / 2.80
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	113.640, 113.640, 185.970, 90.00, 90.00, 120.00
R / Rfree (%)	23 / 26.8

The binding sites of Zinc atom in the Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP (pdb code 6slm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP, PDB code: 6slm:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1201 b:42.7 occ:1.00 SG A:CYS1106 2.3 47.1 1.0 SG A:CYS1136 2.3 50.1 1.0 SG A:CYS1139 2.3 60.4 1.0 SG A:CYS1103 2.3 54.3 1.0 CB A:CYS1103 3.2 39.2 1.0 CB A:CYS1139 3.2 48.7 1.0 CB A:CYS1106 3.3 44.2 1.0 CB A:CYS1136 3.7 47.7 1.0 N A:CYS1106 3.9 36.5 1.0 N A:CYS1139 4.1 57.1 1.0 CA A:CYS1106 4.2 36.2 1.0 N A:CYS1136 4.2 39.1 1.0 CA A:CYS1139 4.3 57.4 1.0 CA A:CYS1136 4.5 40.8 1.0 OG1 A:THR1105 4.6 42.2 1.0 CA A:CYS1103 4.6 37.8 1.0 C A:CYS1106 4.7 39.5 1.0 CG2 A:THR1105 4.9 44.5 1.0 CB A:ARG1108 4.9 49.0 1.0 N A:GLN1107 4.9 40.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1202 b:53.3 occ:1.00 SG A:CYS1066 2.3 49.7 1.0 SG A:CYS1063 2.3 45.5 1.0 SG A:CYS1033 2.3 65.4 1.0 SG A:CYS1030 2.3 46.7 1.0 CB A:CYS1030 3.0 42.8 1.0 CB A:CYS1033 3.2 68.2 1.0 CB A:CYS1066 3.2 38.4 1.0 CB A:CYS1063 3.6 37.0 1.0 N A:CYS1033 3.6 62.4 1.0 CA A:CYS1033 3.9 68.0 1.0 N A:CYS1063 4.1 41.6 1.0 N A:CYS1066 4.4 46.1 1.0 CA A:CYS1063 4.4 34.7 1.0 CA A:CYS1066 4.4 39.3 1.0 CB A:TYR1032 4.4 50.5 1.0 CA A:CYS1030 4.5 43.0 1.0 C A:GLY1153 4.5 0.1 1.0 C A:TYR1032 4.6 56.6 1.0 C A:CYS1033 4.7 65.9 1.0 N A:TYR1032 4.9 48.9 1.0 CA A:GLY1153 4.9 0.8 1.0 CA A:TYR1032 4.9 50.7 1.0 N A:LYS1034 4.9 65.9 1.0 C A:CYS1030 5.0 43.0 1.0

M.Conrady, C.Simon, A.Cousido-Siah, G.Gogl, G.Trave, A.Mitschler. Crystal Structure of Full-Length HPV31 E6 Oncoprotein in Complex with Lxxll Peptide of Ubiquitin Ligase E6AP To Be Published.