Atomistry » Zinc » PDB 6sdj-6sj1 » 6sfu
Atomistry »
  Zinc »
    PDB 6sdj-6sj1 »
      6sfu »

Zinc in PDB 6sfu: Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide

Enzymatic activity of Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide

All present enzymatic activity of Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide:
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide, PDB code: 6sfu was solved by S.Gloeckner, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.24 / 1.04
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.447, 41.620, 72.401, 90.00, 104.56, 90.00
R / Rfree (%) 12.6 / 13.8

Other elements in 6sfu:

The structure of Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide also contains other interesting chemical elements:

Mercury (Hg) 2 atoms
Sodium (Na) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide (pdb code 6sfu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide, PDB code: 6sfu:

Zinc binding site 1 out of 1 in 6sfu

Go back to Zinc Binding Sites List in 6sfu
Zinc binding site 1 out of 1 in the Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:5.2
occ:1.00
 N A:LBQ308 1.9 6.0 1.0
NE2 A:HIS94 2.0 5.8 1.0
ND1 A:HIS119 2.0 5.0 1.0
NE2 A:HIS96 2.0 5.5 1.0
CE1 A:HIS119 2.9 5.2 1.0
O A:LBQ308 3.0 6.5 1.0
CD2 A:HIS94 3.0 5.7 1.0
CD2 A:HIS96 3.0 5.5 1.0
S A:LBQ308 3.0 5.8 1.0
CE1 A:HIS94 3.0 5.8 1.0
HE1 A:HIS119 3.1 6.2 1.0
CE1 A:HIS96 3.1 6.1 1.0
CG A:HIS119 3.1 4.9 1.0
HD2 A:HIS96 3.2 6.6 1.0
HD2 A:HIS94 3.2 6.8 1.0
HB2 A:HIS119 3.2 6.0 1.0
HE1 A:HIS94 3.2 7.0 1.0
HE1 A:HIS96 3.3 7.4 1.0
HG1 A:THR199 3.5 6.6 1.0
CB A:HIS119 3.6 5.0 1.0
O A:HOH562 3.7 15.7 1.0
HB3 A:HIS119 3.7 6.0 1.0
OG1 A:THR199 3.9 5.5 1.0
OE1 A:GLU106 4.0 5.9 1.0
O1 A:LBQ308 4.1 6.2 1.0
NE2 A:HIS119 4.1 5.2 1.0
ND1 A:HIS94 4.1 5.5 1.0
ND1 A:HIS96 4.2 6.6 1.0
CG A:HIS94 4.2 5.5 1.0
C A:LBQ308 4.2 7.1 1.0
CG A:HIS96 4.2 5.7 1.0
CD2 A:HIS119 4.2 5.1 1.0
HH2 A:TRP209 4.2 7.7 1.0
C10 A:LBQ308 4.8 9.0 1.0
HE2 A:HIS119 4.9 6.2 1.0
CD A:GLU106 4.9 5.9 1.0
HG23 A:THR200 4.9 12.7 1.0
HD1 A:HIS94 4.9 6.6 1.0
HG11 A:VAL143 4.9 8.0 1.0
HD1 A:HIS96 4.9 7.9 1.0
C1 A:LBQ308 5.0 8.1 1.0

Reference:

S.Gloeckner, A.Heine, G.Klebe. Human Carbonic Anhydrase II in Complex with A Furan-Containing Benzenesulfonamide To Be Published.
Page generated: Tue Oct 29 07:20:49 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy