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Zinc in PDB 6ri7: Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor

Enzymatic activity of Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor

All present enzymatic activity of Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor:
2.7.7.6;

Other elements in 6ri7:

The structure of Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor (pdb code 6ri7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor, PDB code: 6ri7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 6ri7

Go back to Zinc Binding Sites List in 6ri7
Zinc binding site 1 out of 2 in the Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1501

b:0.0
occ:1.00
SG D:CYS88 2.2 0.2 1.0
SG D:CYS72 2.3 0.4 1.0
CB D:CYS72 2.4 0.4 1.0
SG D:CYS70 2.5 0.8 1.0
SG D:CYS85 2.5 0.5 1.0
N D:CYS72 3.0 0.4 1.0
CA D:CYS72 3.3 0.4 1.0
CB D:CYS88 3.3 0.2 1.0
N D:CYS88 3.4 0.2 1.0
CB D:CYS85 3.4 0.5 1.0
CA D:CYS88 3.9 0.2 1.0
CB D:LYS87 4.1 0.7 1.0
CB D:CYS70 4.2 0.8 1.0
C D:LEU71 4.2 0.8 1.0
C D:CYS72 4.2 0.4 1.0
N D:LEU71 4.3 0.8 1.0
N D:GLY89 4.4 0.6 1.0
C D:LYS87 4.4 0.7 1.0
N D:GLY73 4.5 0.8 1.0
C D:CYS88 4.5 0.2 1.0
CA D:LYS87 4.7 0.7 1.0
CA D:LEU71 4.7 0.8 1.0
N D:LYS87 4.7 0.7 1.0
CA D:CYS85 4.9 0.5 1.0
CB D:LEU71 4.9 0.8 1.0

Zinc binding site 2 out of 2 in 6ri7

Go back to Zinc Binding Sites List in 6ri7
Zinc binding site 2 out of 2 in the Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of E. Coli Rna Polymerase Elongation Complex Bound to Greb Transcription Factor within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn1502

b:0.8
occ:1.00
SG D:CYS888 2.2 82.9 1.0
SG D:CYS898 2.3 67.8 1.0
SG D:CYS895 2.3 76.1 1.0
SG D:CYS814 2.3 77.2 1.0
CB D:CYS888 2.6 82.9 1.0
CB D:CYS814 2.8 77.2 1.0
NH2 D:ARG883 3.0 70.6 1.0
CA D:CYS888 3.2 82.9 1.0
CB D:CYS898 3.3 67.8 1.0
CB D:CYS895 3.4 76.1 1.0
N D:ASP889 3.8 87.7 1.0
C D:CYS888 4.0 82.9 1.0
CZ D:ARG883 4.1 70.6 1.0
CA D:CYS814 4.1 77.2 1.0
N D:CYS814 4.3 77.2 1.0
OG1 D:THR890 4.4 86.2 1.0
N D:CYS888 4.4 82.9 1.0
N D:CYS895 4.4 76.1 1.0
NE D:ARG883 4.4 70.6 1.0
CA D:CYS895 4.4 76.1 1.0
CA D:CYS898 4.5 67.8 1.0
N D:CYS898 4.5 67.8 1.0
OG1 D:THR816 4.8 84.9 1.0
O D:CYS895 4.8 76.1 1.0
C D:CYS895 4.9 76.1 1.0

Reference:

M.Abdelkareem, C.Saint-Andre, M.Takacs, G.Papai, C.Crucifix, X.Guo, J.Ortiz, A.Weixlbaumer. Structural Basis of Transcription: Rna Polymerase Backtracking and Its Reactivation. Mol.Cell V. 75 298 2019.
ISSN: ISSN 1097-2765
PubMed: 31103420
DOI: 10.1016/J.MOLCEL.2019.04.029
Page generated: Tue Oct 29 06:34:08 2024

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