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Atomistry » Zinc » PDB 6p6g-6pi1 » 6p6r | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 6p6g-6pi1 » 6p6r » |
Zinc in PDB 6p6r: Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with GlecaprevirEnzymatic activity of Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir
All present enzymatic activity of Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir:
3.4.21.98; 3.6.1.15; 3.6.4.13; Protein crystallography data
The structure of Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir, PDB code: 6p6r
was solved by
J.Timm,
C.A.Schiffer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6p6r:
The structure of Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir
(pdb code 6p6r). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir, PDB code: 6p6r: Zinc binding site 1 out of 1 in 6p6rGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Hcv NS3/4A Protease Domain of Genotype 1A3A Chimera in Complex with Glecaprevir
![]() Mono view ![]() Stereo pair view
Reference:
J.Timm,
K.Kosovrasti,
M.Henes,
F.Leidner,
S.Hou,
N.Kurt-Yilmaz,
C.A.Schiffer.
Molecular Mechanism of Pan-Genotypic Hcv NS3/4A Protease Inhibition By Glecaprevir and Characterization of Genotype-Specific Structural Differences To Be Published.
Page generated: Tue Oct 29 04:52:03 2024
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