Zinc in PDB 6oum: Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B

All present enzymatic activity of Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B:
4.2.1.1;

The structure of Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B, PDB code: 6oum was solved by A.Kota, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.00 / 1.56
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	41.953, 41.225, 71.976, 90.00, 103.89, 90.00
R / Rfree (%)	25.3 / 30.4

The binding sites of Zinc atom in the Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B (pdb code 6oum). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B, PDB code: 6oum:

Zinc binding site 1 out of 1 in the Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB10- 580B within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:10.1 occ:1.00 NE2 A:HIS96 2.0 10.4 1.0 NAJ A:N7J302 2.0 5.4 1.0 NE2 A:HIS94 2.0 10.0 1.0 ND1 A:HIS119 2.1 8.9 1.0 CD2 A:HIS96 2.8 8.9 1.0 CD2 A:HIS94 2.9 13.0 1.0 CE1 A:HIS119 2.9 10.3 1.0 CE1 A:HIS96 3.0 13.3 1.0 SAG A:N7J302 3.1 12.7 1.0 CE1 A:HIS94 3.1 11.7 1.0 OAH A:N7J302 3.1 11.1 1.0 CG A:HIS119 3.2 12.2 1.0 CB A:HIS119 3.6 8.3 1.0 O A:HOH479 3.7 11.4 1.0 OG1 A:THR199 3.9 5.6 1.0 OE1 A:GLU106 3.9 13.1 1.0 CG A:HIS96 4.0 4.6 1.0 ND1 A:HIS96 4.1 9.5 1.0 CG A:HIS94 4.1 7.4 1.0 NE2 A:HIS119 4.1 7.5 1.0 ND1 A:HIS94 4.1 12.9 1.0 OAI A:N7J302 4.2 9.2 1.0 CD2 A:HIS119 4.2 15.9 1.0 CAF A:N7J302 4.3 11.8 1.0 O A:HOH456 4.4 18.3 1.0 CD A:GLU106 4.8 16.1 1.0 CAA A:N7J302 4.9 13.9 1.0

A.Kota, R.Mckenna. Carbonic Anhydrase IX Mimic Complexed with Ureido Benzene Sulfonamide MB10-580B To Be Published.