Zinc in PDB 6oui: Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A

All present enzymatic activity of Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A:
4.2.1.1;

The structure of Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A, PDB code: 6oui was solved by A.Kota, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.09 / 1.53
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.334, 42.083, 71.906, 90.00, 104.21, 90.00
R / Rfree (%)	17.7 / 20.7

The binding sites of Zinc atom in the Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A (pdb code 6oui). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A, PDB code: 6oui:

Zinc binding site 1 out of 1 in the Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase IX Mimic Complexed with Benzene Sulfonamide MB11- 710A within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:11.5 occ:1.00 NAJ A:N7D302 2.0 12.1 1.0 NE2 A:HIS94 2.0 10.6 1.0 NE2 A:HIS96 2.1 11.1 1.0 ND1 A:HIS119 2.1 10.8 1.0 CE1 A:HIS119 2.9 9.9 1.0 CD2 A:HIS94 3.0 12.3 1.0 CD2 A:HIS96 3.0 11.3 1.0 OAI A:N7D302 3.0 10.4 1.0 SAG A:N7D302 3.0 12.0 1.0 CE1 A:HIS94 3.0 12.6 1.0 CE1 A:HIS96 3.1 10.6 1.0 CG A:HIS119 3.2 8.9 1.0 CB A:HIS119 3.6 8.5 1.0 OG1 A:THR199 3.8 12.2 1.0 O A:HOH583 3.9 20.1 1.0 OE1 A:GLU106 3.9 10.8 1.0 NE2 A:HIS119 4.1 10.0 1.0 ND1 A:HIS94 4.1 13.8 1.0 CG A:HIS94 4.1 12.6 1.0 ND1 A:HIS96 4.2 10.8 1.0 CG A:HIS96 4.2 11.7 1.0 OAH A:N7D302 4.2 11.9 1.0 CAE A:N7D302 4.2 12.3 1.0 CD2 A:HIS119 4.2 8.4 1.0 CAD A:N7D302 4.8 14.4 1.0 O A:HOH479 4.8 31.7 1.0 CD A:GLU106 4.9 12.8 1.0

A.Kota, R.Mckenna. Carbonic Anhydrase IX Mimic Complexed with Ureido Benzene Sulfonamide MB11-710A To Be Published.