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Zinc in PDB 6oip: Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34
Enzymatic activity of Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34
All present enzymatic activity of Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34:
2.3.1.48;
2.3.1.48;
Protein crystallography data
The structure of Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34, PDB code: 6oip
was solved by
S.J.Hermans,
M.C.Chung,
M.W.Parker,
T.Thomas,
J.B.Baell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 34.31 / 1.80 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 46.400, 55.920, 123.950, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 18.5 / 22.2 |
Other elements in 6oip:
The structure of Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34 also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34
(pdb code 6oip). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34, PDB code: 6oip:
In total only one binding site of Zinc was determined in the Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34, PDB code: 6oip:
Zinc binding site 1 out of 1 in 6oip
Go back to
Zinc Binding Sites List in 6oip
Zinc binding site 1 out
of 1 in the Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Myst Acetyltransferase Domain in Complex with Inhibitor 34 within 5.0Å range:
|
Reference:
D.J.Leaver,
B.Cleary,
N.Nguyen,
D.L.Priebbenow,
H.R.Lagiakos,
J.Sanchez,
L.Xue,
F.Huang,
Y.Sun,
P.Mujumdar,
R.Mudududdla,
S.Varghese,
S.Teguh,
S.A.Charman,
K.L.White,
K.Katneni,
M.Cuellar,
J.M.Strasser,
J.L.Dahlin,
M.A.Walters,
I.P.Street,
B.J.Monahan,
K.E.Jarman,
H.J.Sabroux,
H.Falk,
M.C.Chung,
S.J.Hermans,
M.W.Parker,
T.Thomas,
J.B.Baell.
Discovery of Benzoylsulfonohydrazides As Potent Inhibitors of the Histone Acetyltransferase KAT6A. J.Med.Chem. V. 62 7146 2019.
ISSN: ISSN 0022-2623
PubMed: 31256587
DOI: 10.1021/ACS.JMEDCHEM.9B00665
Page generated: Tue Oct 29 04:24:35 2024
ISSN: ISSN 0022-2623
PubMed: 31256587
DOI: 10.1021/ACS.JMEDCHEM.9B00665
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