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Atomistry » Zinc » PDB 6n9a-6ngk » 6nfo » |
Zinc in PDB 6nfo: Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-CarboxamideEnzymatic activity of Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide
All present enzymatic activity of Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide:
2.7.7.86; Protein crystallography data
The structure of Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide, PDB code: 6nfo
was solved by
J.Hall,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide
(pdb code 6nfo). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide, PDB code: 6nfo: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 6nfoGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 6nfoGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Cyclic Gmp-Amp Synthase in Complex with Compound 20 Inhibitor: 7- Hydroxy-N-[(2S)-1-Hydroxypropan-2-Yl]-5-Phenylpyrazolo[1,5- A]Pyrimidine-3-Carboxamide
![]() Mono view ![]() Stereo pair view
Reference:
J.Hall,
J.Hall.
N/A N/A.
Page generated: Tue Oct 29 03:41:55 2024
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