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Zinc in PDB 6klk: Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Enzymatic activity of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
All present enzymatic activity of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu:
3.5.2.2;
3.5.2.2;
Protein crystallography data
The structure of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu, PDB code: 6klk
was solved by
Y.H.Huang,
I.C.Chen,
C.Y.Huang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 27.83 / 1.76 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 111.333, 111.333, 159.977, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 18.5 / 21.2 |
Other elements in 6klk:
The structure of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
(pdb code 6klk). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu, PDB code: 6klk:
Jump to Zinc binding site number: 1; 2; 3; 4;
In total 4 binding sites of Zinc where determined in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu, PDB code: 6klk:
Jump to Zinc binding site number: 1; 2; 3; 4;
Zinc binding site 1 out of 4 in 6klk
Go back to
Zinc Binding Sites List in 6klk
Zinc binding site 1 out
of 4 in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu within 5.0Å range:
|
Zinc binding site 2 out of 4 in 6klk
Go back to
Zinc Binding Sites List in 6klk
Zinc binding site 2 out
of 4 in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu within 5.0Å range:
|
Zinc binding site 3 out of 4 in 6klk
Go back to
Zinc Binding Sites List in 6klk
Zinc binding site 3 out
of 4 in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu within 5.0Å range:
|
Zinc binding site 4 out of 4 in 6klk
Go back to
Zinc Binding Sites List in 6klk
Zinc binding site 4 out
of 4 in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu within 5.0Å range:
|
Reference:
Y.H.Huang,
Z.J.Ning,
C.Y.Huang.
Crystal Structure of Dihydropyrimidinase in Complex with Anticancer Drug 5-Fluorouracil. Biochem.Biophys.Res.Commun. V. 519 160 2019.
ISSN: ESSN 1090-2104
PubMed: 31481233
DOI: 10.1016/J.BBRC.2019.08.153
Page generated: Tue Oct 29 01:49:59 2024
ISSN: ESSN 1090-2104
PubMed: 31481233
DOI: 10.1016/J.BBRC.2019.08.153
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