Zinc in PDB 6kiv: Cryo-Em Structure of Human MLL1-Ubncp Complex (4.0 Angstrom)

All present enzymatic activity of Cryo-Em Structure of Human MLL1-Ubncp Complex (4.0 Angstrom):
2.1.1.43;

The binding sites of Zinc atom in the Cryo-Em Structure of Human MLL1-Ubncp Complex (4.0 Angstrom) (pdb code 6kiv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Human MLL1-Ubncp Complex (4.0 Angstrom), PDB code: 6kiv:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Human MLL1-Ubncp Complex (4.0 Angstrom)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human MLL1-Ubncp Complex (4.0 Angstrom) within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn4002 b:0.8 occ:1.00 SG K:CYS3957 2.5 0.9 1.0 SG K:CYS3959 2.5 0.7 1.0 SG K:CYS3964 3.6 0.3 1.0 CB K:CYS3957 3.7 0.9 1.0 O K:PHE3967 3.9 0.5 1.0 CD2 K:HIS3907 4.0 0.9 1.0 CA K:CYS3957 4.3 0.9 1.0 CB K:CYS3959 4.3 0.7 1.0 C K:PHE3967 4.3 0.5 1.0 CD1 K:LEU3968 4.4 0.9 1.0 N K:LEU3968 4.7 0.9 1.0 N K:GLY3960 4.7 0.5 1.0 CG K:LEU3968 4.7 0.9 1.0 N K:CYS3959 4.8 0.7 1.0 CG K:HIS3907 4.8 0.9 1.0 CB K:CYS3964 4.8 0.3 1.0 C K:CYS3957 4.9 0.9 1.0 N K:PHE3967 4.9 0.5 1.0 CA K:LEU3968 4.9 0.9 1.0 NE2 K:HIS3907 5.0 0.9 1.0 CA K:CYS3959 5.0 0.7 1.0

H.Xue, T.Yao, M.Cao, G.Zhu, Y.Li, G.Yuan, Y.Chen, M.Lei, J.Huang. Structural Basis of Nucleosome Recognition and Modification By Mll Methyltransferases. Nature V. 573 445 2019.
ISSN: ESSN 1476-4687
PubMed: 31485071
DOI: 10.1038/S41586-019-1528-1