Zinc in PDB 6k4t: Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa

All present enzymatic activity of Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa:
3.5.2.6;

The structure of Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa, PDB code: 6k4t was solved by J.Wachino, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.66 / 1.39
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	37.040, 41.590, 45.550, 108.60, 102.75, 106.06
R / Rfree (%)	14.7 / 17

The binding sites of Zinc atom in the Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa (pdb code 6k4t). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa, PDB code: 6k4t:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:7.1 occ:1.00 NE2 A:HIS72 2.0 6.7 1.0 NE2 A:HIS150 2.1 5.7 1.0 ND1 A:HIS74 2.1 8.6 1.0 SD A:JKE303 2.2 10.0 1.0 CD2 A:HIS150 3.0 6.3 1.0 CD2 A:HIS72 3.0 6.8 1.0 CE1 A:HIS74 3.0 7.8 1.0 CE1 A:HIS72 3.0 6.5 1.0 CE1 A:HIS150 3.1 6.0 1.0 CG A:HIS74 3.2 6.8 1.0 CE1 A:JKE303 3.3 9.7 1.0 OD2 A:JKE303 3.3 9.8 1.0 CB A:HIS74 3.6 7.7 1.0 ZN A:ZN302 3.7 7.9 1.0 CG A:JKE303 3.8 9.7 1.0 CZ A:JKE303 3.9 9.6 1.0 ND1 A:HIS72 4.1 6.8 1.0 CG A:HIS72 4.1 6.4 1.0 CG A:HIS150 4.2 6.2 1.0 NE2 A:HIS74 4.2 7.7 1.0 CD2 A:HIS77 4.2 7.2 1.0 ND1 A:HIS150 4.2 6.5 1.0 CD1 A:JKE303 4.2 10.0 1.0 CD2 A:HIS74 4.2 6.5 1.0 NE2 A:HIS77 4.2 6.3 1.0 OE1 A:GLN113 4.3 11.3 1.0 OD1 A:ASP76 4.3 8.3 1.0 OD1 A:JKE303 4.8 9.7 1.0 O A:HOH606 4.8 21.5 1.0 CA A:HIS74 4.9 7.1 1.0 OD2 A:ASP76 5.0 7.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Smb-1 Metallo-Beta-Lactamase in A Complex with Tsa within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:7.9 occ:1.00 NE2 A:HIS77 2.0 6.3 1.0 OD2 A:ASP76 2.1 7.5 1.0 NE2 A:HIS215 2.1 6.9 1.0 SD A:JKE303 2.3 10.0 1.0 OD2 A:JKE303 2.3 9.8 1.0 CG A:ASP76 2.9 6.8 1.0 CE1 A:HIS77 3.0 7.4 1.0 CD2 A:HIS77 3.0 7.2 1.0 CD2 A:HIS215 3.0 6.3 1.0 CE1 A:HIS215 3.0 7.1 1.0 OD1 A:ASP76 3.2 8.3 1.0 CG A:JKE303 3.2 9.7 1.0 CE1 A:JKE303 3.2 9.7 1.0 CZ A:JKE303 3.5 9.6 1.0 ZN A:ZN301 3.7 7.1 1.0 ND1 A:HIS77 4.1 6.9 1.0 CG A:HIS77 4.1 7.4 1.0 ND1 A:HIS215 4.1 7.2 1.0 CG A:HIS215 4.2 6.4 1.0 NE2 A:HIS72 4.2 6.7 1.0 CE1 A:HIS72 4.2 6.5 1.0 OD1 A:JKE303 4.3 9.7 1.0 CB A:ASP76 4.3 6.9 1.0 CD1 A:JKE303 4.4 10.0 1.0 OG A:SER175 4.4 4.7 0.5 CE2 A:JKE303 4.8 10.6 1.0 O A:HOH712 4.8 27.4 1.0 CD1 A:ILE26 4.9 8.7 1.0 O A:HOH606 4.9 21.5 1.0 NE2 A:HIS150 5.0 5.7 1.0

J.Wachino, J.Wachino. N/A N/A.