Zinc in PDB 6iq1: Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans

The structure of Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans, PDB code: 6iq1 was solved by A.Jung, J.-S.Yun, J.H.Chang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.93 / 2.49
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.354, 101.907, 175.175, 90.00, 90.00, 90.00
R / Rfree (%)	18.8 / 22.8

The binding sites of Zinc atom in the Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans (pdb code 6iq1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans, PDB code: 6iq1:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:39.0 occ:1.00 ND1 A:HIS104 2.1 28.5 1.0 ND1 A:HIS49 2.2 31.3 1.0 SG A:CYS7 2.4 31.1 1.0 SG A:CYS10 2.4 27.8 1.0 CE1 A:HIS104 3.0 25.9 1.0 CG A:HIS49 3.1 34.6 1.0 CE1 A:HIS49 3.1 31.4 1.0 CG A:HIS104 3.2 27.6 1.0 CB A:CYS7 3.2 29.3 1.0 CB A:CYS10 3.4 20.0 1.0 CB A:HIS49 3.4 33.3 1.0 N A:CYS10 3.6 27.2 1.0 CB A:HIS104 3.6 27.2 1.0 CA A:CYS10 4.0 25.1 1.0 NE2 A:HIS104 4.2 31.0 1.0 CA A:HIS49 4.2 32.6 1.0 NE2 A:HIS49 4.3 35.1 1.0 CD2 A:HIS104 4.3 31.2 1.0 CD2 A:HIS49 4.3 36.1 1.0 C A:PHE9 4.6 27.4 1.0 CB A:PHE9 4.6 26.7 1.0 CA A:CYS7 4.6 31.9 1.0 CA A:HIS104 4.9 31.8 1.0 N A:PHE9 4.9 28.1 1.0 C A:CYS7 5.0 29.9 1.0 O A:CYS7 5.0 29.0 1.0 CA A:PHE9 5.0 30.8 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:42.5 occ:1.00 ND1 B:HIS49 2.1 36.1 1.0 ND1 B:HIS104 2.1 33.5 1.0 SG B:CYS7 2.3 33.8 1.0 SG B:CYS10 2.4 29.3 1.0 CE1 B:HIS49 2.9 35.8 1.0 CE1 B:HIS104 3.0 27.3 1.0 CG B:HIS104 3.1 31.3 1.0 CB B:CYS7 3.2 36.6 1.0 CG B:HIS49 3.2 38.9 1.0 CB B:CYS10 3.4 23.6 1.0 CB B:HIS104 3.5 25.1 1.0 N B:CYS10 3.6 30.2 1.0 CB B:HIS49 3.7 34.8 1.0 CA B:CYS10 4.0 26.9 1.0 NE2 B:HIS49 4.1 37.8 1.0 NE2 B:HIS104 4.2 33.9 1.0 CD2 B:HIS104 4.2 33.5 1.0 CD2 B:HIS49 4.3 38.1 1.0 CA B:HIS49 4.3 36.4 1.0 C B:PHE9 4.6 29.9 1.0 CA B:CYS7 4.6 39.5 1.0 CB B:PHE9 4.6 27.7 1.0 CA B:HIS104 4.7 34.2 1.0 ND1 B:HIS4 4.9 57.9 1.0 C B:CYS7 4.9 32.9 1.0 N B:PHE9 4.9 27.6 1.0 CA B:PHE9 4.9 30.0 1.0 O B:CYS7 5.0 33.2 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn201 b:47.9 occ:1.00 ND1 C:HIS49 2.0 34.8 1.0 SG C:CYS7 2.3 36.9 1.0 ND1 C:HIS104 2.3 36.4 1.0 SG C:CYS10 2.5 33.5 1.0 CE1 C:HIS49 2.9 32.6 1.0 CG C:HIS49 3.0 35.4 1.0 CB C:CYS7 3.1 41.4 1.0 CG C:HIS104 3.2 34.8 1.0 CE1 C:HIS104 3.3 33.7 1.0 CB C:HIS49 3.4 34.7 1.0 CB C:HIS104 3.5 35.7 1.0 CB C:CYS10 3.6 33.1 1.0 N C:CYS10 3.6 36.8 1.0 NE2 C:HIS49 4.0 34.3 1.0 CA C:CYS10 4.1 34.6 1.0 CD2 C:HIS49 4.1 34.4 1.0 CA C:HIS49 4.1 38.1 1.0 CD2 C:HIS104 4.4 38.9 1.0 NE2 C:HIS104 4.4 36.1 1.0 CA C:CYS7 4.6 47.4 1.0 C C:PHE9 4.6 38.4 1.0 CB C:PHE9 4.6 36.1 1.0 CA C:HIS104 4.7 38.8 1.0 C C:CYS7 4.9 44.0 1.0 N C:PHE9 4.9 40.8 1.0 O C:CYS7 4.9 40.1 1.0 CA C:PHE9 4.9 37.7 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Histidine Triad Nucleotide-Binding Protein From Candida Albicans within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:46.1 occ:1.00 ND1 D:HIS49 2.0 35.2 1.0 ND1 D:HIS104 2.2 37.1 1.0 SG D:CYS7 2.3 36.0 1.0 SG D:CYS10 2.5 33.6 1.0 CE1 D:HIS49 2.8 32.0 1.0 CG D:HIS49 3.2 32.8 1.0 CB D:CYS7 3.2 42.0 1.0 CE1 D:HIS104 3.2 34.9 1.0 CG D:HIS104 3.2 36.8 1.0 CB D:HIS104 3.5 31.6 1.0 CB D:CYS10 3.5 31.3 1.0 N D:CYS10 3.5 33.7 1.0 CB D:HIS49 3.6 34.9 1.0 CA D:CYS10 4.0 34.2 1.0 NE2 D:HIS49 4.0 32.4 1.0 CD2 D:HIS49 4.2 33.7 1.0 CA D:HIS49 4.3 34.2 1.0 NE2 D:HIS104 4.3 34.6 1.0 CD2 D:HIS104 4.4 38.2 1.0 C D:PHE9 4.5 34.4 1.0 O D:HOH301 4.5 53.2 1.0 CB D:PHE9 4.5 33.4 1.0 CA D:CYS7 4.6 42.6 1.0 CA D:HIS104 4.7 35.2 1.0 CA D:PHE9 4.9 36.4 1.0 O D:CYS7 4.9 39.1 1.0 N D:PHE9 4.9 34.6 1.0 C D:CYS7 4.9 36.3 1.0

A.Jung, J.S.Yun, S.Kim, S.R.Kim, M.Shin, D.H.Cho, K.S.Choi, J.H.Chang. Crystal Structure of Histidine Triad Nucleotide-Binding Protein From the Pathogenic Funguscandida Albicans. Mol. Cells V. 42 56 2019.
ISSN: ISSN 0219-1032
PubMed: 30622225
DOI: 10.14348/MOLCELLS.2018.0377