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Zinc in PDB 6ii7: Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine
Enzymatic activity of Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine
All present enzymatic activity of Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine:
3.5.4.4;
3.5.4.4;
Protein crystallography data
The structure of Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine, PDB code: 6ii7
was solved by
P.Chitnumsub,
A.Jaruwat,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 50.00 / 2.48 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 48.605, 62.553, 126.703, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17.3 / 23.9 |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine
(pdb code 6ii7). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine, PDB code: 6ii7:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine, PDB code: 6ii7:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 6ii7
Go back to
Zinc Binding Sites List in 6ii7
Zinc binding site 1 out
of 2 in the Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine within 5.0Å range:
|
Zinc binding site 2 out of 2 in 6ii7
Go back to
Zinc Binding Sites List in 6ii7
Zinc binding site 2 out
of 2 in the Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Plasmodium Falciparum Adenosine Deaminase C27Q+L227I Mutant Co-Complexed with Zn Ion, Hypoxanthine and Inosine within 5.0Å range:
|
Reference:
A.Jaruwat,
P.Riangrungroj,
S.Ubonprasert,
U.Sae-Ueng,
B.Kuaprasert,
Y.Yuthavong,
U.Leartsakulpanich,
P.Chitnumsub.
Crystal Structure of Plasmodium Falciparum Adenosine Deaminase Reveals A Novel Binding Pocket For Inosine. Arch. Biochem. Biophys. V. 667 6 2019.
ISSN: ESSN 1096-0384
PubMed: 31002765
DOI: 10.1016/J.ABB.2019.04.002
Page generated: Mon Oct 28 23:49:57 2024
ISSN: ESSN 1096-0384
PubMed: 31002765
DOI: 10.1016/J.ABB.2019.04.002
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