Atomistry » Zinc » PDB 6i0w-6iiw » 6i0w
Atomistry »
  Zinc »
    PDB 6i0w-6iiw »
      6i0w »

Zinc in PDB 6i0w: Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide

Enzymatic activity of Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide

All present enzymatic activity of Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide:
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide, PDB code: 6i0w was solved by S.Gloeckner, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.96 / 1.04
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.375, 41.427, 72.258, 90.00, 104.63, 90.00
R / Rfree (%) 11.9 / 13.2

Other elements in 6i0w:

The structure of Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide also contains other interesting chemical elements:

Mercury (Hg) 3 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide (pdb code 6i0w). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide, PDB code: 6i0w:

Zinc binding site 1 out of 1 in 6i0w

Go back to Zinc Binding Sites List in 6i0w
Zinc binding site 1 out of 1 in the Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Carbonic Anhydrase II in Complex with 4- Methoxybenzenesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:6.3
occ:1.00
 N1 A:M4S308 2.0 7.0 1.0
NE2 A:HIS94 2.0 6.5 1.0
ND1 A:HIS119 2.0 5.9 1.0
NE2 A:HIS96 2.0 6.5 1.0
CE1 A:HIS119 2.9 6.0 1.0
CD2 A:HIS96 3.0 6.5 1.0
CD2 A:HIS94 3.0 6.7 1.0
O3 A:M4S308 3.0 8.1 1.0
HE1 A:HIS119 3.0 7.2 1.0
CE1 A:HIS94 3.0 6.6 1.0
S1 A:M4S308 3.1 7.3 1.0
CE1 A:HIS96 3.1 7.1 1.0
CG A:HIS119 3.1 5.7 1.0
HD2 A:HIS96 3.1 7.8 1.0
HD2 A:HIS94 3.2 8.0 1.0
HB2 A:HIS119 3.2 7.2 1.0
HE1 A:HIS94 3.2 7.9 1.0
HE1 A:HIS96 3.3 8.5 1.0
HG1 A:THR199 3.5 8.0 1.0
CB A:HIS119 3.6 6.0 1.0
O A:HOH564 3.7 12.3 1.0
HB3 A:HIS119 3.7 7.2 1.0
OG1 A:THR199 3.8 6.6 1.0
OE1 A:GLU106 4.0 6.8 1.0
O2 A:M4S308 4.1 7.6 1.0
NE2 A:HIS119 4.1 6.1 1.0
ND1 A:HIS94 4.1 6.8 1.0
ND1 A:HIS96 4.2 7.7 1.0
CG A:HIS94 4.2 6.7 1.0
CG A:HIS96 4.2 6.7 1.0
CD2 A:HIS119 4.2 5.9 1.0
C5 A:M4S308 4.2 8.3 1.0
HH2 A:TRP209 4.2 8.3 1.0
O A:HOH592 4.6 17.5 1.0
HE2 A:HIS119 4.8 7.3 1.0
C1 A:M4S308 4.9 9.1 1.0
CD A:GLU106 4.9 7.0 1.0
HG23 A:THR200 4.9 12.9 1.0
HD1 A:HIS94 4.9 8.1 1.0
HD1 A:HIS96 4.9 9.2 1.0
HG11 A:VAL143 5.0 8.6 1.0

Reference:

S.Gloeckner, A.Heine, G.Klebe. Human Carbonic Anhydrase II in Complex with 4-Methoxybenzenesulfonamide To Be Published.
Page generated: Mon Oct 28 23:34:39 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy