Atomistry » Zinc » PDB 6hrg-6i0l » 6hxd
Atomistry »
  Zinc »
    PDB 6hrg-6i0l »
      6hxd »

Zinc in PDB 6hxd: Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide

Enzymatic activity of Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide

All present enzymatic activity of Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide:
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide, PDB code: 6hxd was solved by S.Gloeckner, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 22.84 / 1.12
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.237, 41.498, 72.142, 90.00, 104.53, 90.00
R / Rfree (%) 11.5 / 13.1

Other elements in 6hxd:

The structure of Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide also contains other interesting chemical elements:

Mercury (Hg) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide (pdb code 6hxd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide, PDB code: 6hxd:

Zinc binding site 1 out of 1 in 6hxd

Go back to Zinc Binding Sites List in 6hxd
Zinc binding site 1 out of 1 in the Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn301

b:6.1
occ:1.00
 N A:6YP305 2.0 6.9 1.0
NE2 A:HIS94 2.0 6.9 1.0
NE2 A:HIS96 2.0 6.5 1.0
ND1 A:HIS119 2.0 5.8 1.0
CE1 A:HIS119 2.9 5.7 1.0
CD2 A:HIS94 3.0 6.6 1.0
O1 A:6YP305 3.0 7.7 1.0
CD2 A:HIS96 3.0 6.3 1.0
CE1 A:HIS94 3.0 6.5 1.0
S A:6YP305 3.0 7.1 1.0
HE1 A:HIS119 3.0 6.8 1.0
CE1 A:HIS96 3.0 7.0 1.0
CG A:HIS119 3.1 5.6 1.0
HD2 A:HIS94 3.2 8.0 1.0
HD2 A:HIS96 3.2 7.6 1.0
HB2 A:HIS119 3.2 7.0 1.0
HE1 A:HIS94 3.2 7.8 1.0
HE1 A:HIS96 3.3 8.4 1.0
HG1 A:THR199 3.5 7.9 1.0
CB A:HIS119 3.6 5.8 1.0
O A:HOH578 3.7 19.6 1.0
HB3 A:HIS119 3.7 7.0 1.0
OG1 A:THR199 3.9 6.6 1.0
OE1 A:GLU106 4.0 6.8 1.0
O A:6YP305 4.1 7.5 1.0
NE2 A:HIS119 4.1 6.1 1.0
ND1 A:HIS94 4.1 7.3 1.0
CG A:HIS94 4.2 7.0 1.0
ND1 A:HIS96 4.2 7.6 1.0
CG A:HIS96 4.2 6.6 1.0
C7 A:6YP305 4.2 8.3 1.0
CD2 A:HIS119 4.2 5.9 1.0
HH2 A:TRP209 4.2 8.4 1.0
HG23 A:THR200 4.8 13.3 1.0
C6 A:6YP305 4.8 10.0 1.0
HE2 A:HIS119 4.9 7.3 1.0
HD1 A:HIS94 4.9 8.8 1.0
CD A:GLU106 4.9 6.9 1.0
HD1 A:HIS96 4.9 9.1 1.0
HG11 A:VAL143 5.0 8.1 1.0
C8 A:6YP305 5.0 9.4 1.0

Reference:

S.Gloeckner, A.Heine, G.Klebe. Human Carbonic Anhydrase II in Complex with 4-Butylbenzenesulfonamide To Be Published.
Page generated: Mon Oct 28 23:26:46 2024

Last articles

Na in 1KEJ
Na in 1KDH
Na in 1K8A
Na in 1KCC
Na in 1KC6
Na in 1KA0
Na in 1K8Y
Na in 1K8Z
Na in 1K8X
Na in 1K7X
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy