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Atomistry » Zinc » PDB 6h0w-6h52 » 6h50 » |
Zinc in PDB 6h50: Crystal Structure of Human KDM5B in Complex with Compound 34AProtein crystallography data
The structure of Crystal Structure of Human KDM5B in Complex with Compound 34A, PDB code: 6h50
was solved by
Y.V.Le Bihan,
S.Velupillai,
R.L.M.Van Montfort,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6h50:
The structure of Crystal Structure of Human KDM5B in Complex with Compound 34A also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human KDM5B in Complex with Compound 34A
(pdb code 6h50). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human KDM5B in Complex with Compound 34A, PDB code: 6h50: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 6h50Go back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of Human KDM5B in Complex with Compound 34A
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 6h50Go back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of Human KDM5B in Complex with Compound 34A
![]() Mono view ![]() Stereo pair view
Reference:
Y.V.Le Bihan,
R.M.Lanigan,
B.Atrash,
M.G.Mclaughlin,
S.Velupillai,
A.G.Malcolm,
K.S.England,
G.F.Ruda,
N.Y.Mok,
A.Tumber,
K.Tomlin,
H.Saville,
E.Shehu,
C.Mcandrew,
L.Carmichael,
J.M.Bennett,
F.Jeganathan,
P.Eve,
A.Donovan,
A.Hayes,
F.Wood,
F.I.Raynaud,
O.Fedorov,
P.E.Brennan,
R.Burke,
R.L.M.Van Montfort,
O.W.Rossanese,
J.Blagg,
V.Bavetsias.
C8-Substituted Pyrido[3,4-D]Pyrimidin-4(3H)-Ones: Studies Towards the Identification of Potent, Cell Penetrant Jumonji C Domain Containing Histone Lysine Demethylase 4 Subfamily (KDM4) Inhibitors, Compound Profiling in Cell-Based Target Engagement Assays. Eur.J.Med.Chem. V. 177 316 2019.
Page generated: Mon Oct 28 22:34:19 2024
ISSN: ISSN 0223-5234 PubMed: 31158747 DOI: 10.1016/J.EJMECH.2019.05.041 |
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