Zinc in PDB 6g19: Cryoem Structure of the MDA5-Dsrna Filament with 74-Degree Helical Twist

All present enzymatic activity of Cryoem Structure of the MDA5-Dsrna Filament with 74-Degree Helical Twist:
3.6.4.13;

The binding sites of Zinc atom in the Cryoem Structure of the MDA5-Dsrna Filament with 74-Degree Helical Twist (pdb code 6g19). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryoem Structure of the MDA5-Dsrna Filament with 74-Degree Helical Twist, PDB code: 6g19:

Zinc binding site 1 out of 1 in the Cryoem Structure of the MDA5-Dsrna Filament with 74-Degree Helical Twist


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of the MDA5-Dsrna Filament with 74-Degree Helical Twist within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1101 b:86.6 occ:1.00 HG A:CYS907 1.2 65.7 1.0 SG A:CYS964 2.2 66.5 1.0 SG A:CYS910 2.3 67.2 1.0 SG A:CYS962 2.3 65.7 1.0 SG A:CYS907 2.3 65.7 1.0 HG A:CYS910 2.6 67.2 1.0 HB3 A:CYS907 3.1 65.7 1.0 H A:CYS910 3.1 67.2 1.0 HZ2 A:TRP968 3.2 61.2 1.0 CB A:CYS907 3.2 65.7 1.0 CB A:CYS962 3.3 65.7 1.0 HB2 A:CYS907 3.3 65.7 1.0 CB A:CYS964 3.4 66.5 1.0 H A:CYS964 3.5 66.5 1.0 HE2 A:MET912 3.5 67.3 1.0 HE1 A:TRP968 3.5 61.2 1.0 HB3 A:ASN909 3.6 64.1 1.0 CB A:CYS910 3.7 67.2 1.0 HB3 A:CYS910 3.8 67.2 1.0 HB3 A:GLN966 3.9 63.3 1.0 N A:CYS910 3.9 67.2 1.0 CZ2 A:TRP968 4.0 61.2 1.0 HE1 A:MET912 4.1 67.3 1.0 N A:CYS964 4.2 66.5 1.0 NE1 A:TRP968 4.2 61.2 1.0 CE A:MET912 4.2 67.3 1.0 H A:GLN966 4.3 63.3 1.0 O A:CYS910 4.3 67.2 1.0 H A:GLY965 4.3 65.6 1.0 CA A:CYS910 4.4 67.2 1.0 CA A:CYS964 4.4 66.5 1.0 HB2 A:CYS910 4.4 67.2 1.0 CE2 A:TRP968 4.5 61.2 1.0 H A:ASN909 4.5 64.1 1.0 HB3 A:MET912 4.6 67.3 1.0 CB A:ASN909 4.6 64.1 1.0 H A:LYS963 4.6 69.2 1.0 CA A:CYS907 4.6 65.7 1.0 HB2 A:GLN966 4.7 63.3 1.0 CB A:GLN966 4.7 63.3 1.0 CA A:CYS962 4.7 65.7 1.0 C A:CYS910 4.8 67.2 1.0 HE3 A:MET912 4.9 67.3 1.0 HB2 A:ASN909 5.0 64.1 1.0 HA A:CYS907 5.0 65.7 1.0 N A:LYS963 5.0 69.2 1.0 N A:GLY965 5.0 65.6 1.0

Q.Yu, K.Qu, Y.Modis. Cryo-Em Structures of MDA5-Dsrna Filaments at Different Stages of Atp Hydrolysis. Mol. Cell V. 72 999 2018.
ISSN: ISSN 1097-4164
PubMed: 30449722
DOI: 10.1016/J.MOLCEL.2018.10.012