Atomistry » Zinc » PDB 6fnd-6fz7 » 6fv4
Atomistry »
  Zinc »
    PDB 6fnd-6fz7 »
      6fv4 »

Zinc in PDB 6fv4: The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate

Enzymatic activity of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate

All present enzymatic activity of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate:
3.5.1.25;

Protein crystallography data

The structure of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate, PDB code: 6fv4 was solved by M.S.Ahangar, C.M.Furze, C.S.Guy, C.Cooper, K.S.Maskew, B.Graham, A.D.Cameron, E.Fullam, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 54.56 / 1.97
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 164.766, 54.437, 110.262, 90.00, 123.22, 90.00
R / Rfree (%) 18.4 / 23.5

Other elements in 6fv4:

The structure of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate also contains other interesting chemical elements:

Cadmium (Cd) 4 atoms
Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate (pdb code 6fv4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate, PDB code: 6fv4:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 6fv4

Go back to Zinc Binding Sites List in 6fv4
Zinc binding site 1 out of 2 in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:42.4
occ:1.00
 NE2 A:HIS58 2.1 41.4 1.0
OE1 A:GLU122 2.1 39.0 1.0
NE2 A:HIS56 2.1 33.4 1.0
CL A:CL405 2.2 44.7 1.0
CE1 A:HIS58 2.8 36.5 1.0
CE1 A:HIS56 3.0 32.4 1.0
CD A:GLU122 3.0 38.4 1.0
CD2 A:HIS56 3.2 30.8 1.0
CD2 A:HIS58 3.3 34.3 1.0
OE2 A:GLU122 3.4 38.2 1.0
CD A:CD403 3.4 35.5 1.0
C8 A:16G402 3.9 46.3 0.8
ND1 A:HIS58 4.0 36.5 1.0
ND1 A:HIS56 4.2 31.0 1.0
CG A:HIS58 4.3 33.2 1.0
CG A:HIS56 4.3 30.3 1.0
CG A:GLU122 4.4 30.6 1.0
C7 A:16G402 4.4 48.8 0.8
CB A:ALA267 4.4 32.6 1.0
CB A:GLU122 4.6 32.6 1.0
CD2 A:HIS209 4.7 30.7 1.0
N2 A:16G402 4.7 48.5 0.8
NE2 A:HIS209 4.7 33.2 1.0
CB A:SER91 4.8 30.7 1.0
O7 A:16G402 4.9 53.1 0.8
CA A:ALA267 5.0 29.0 1.0

Zinc binding site 2 out of 2 in 6fv4

Go back to Zinc Binding Sites List in 6fv4
Zinc binding site 2 out of 2 in the The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D267A Mutant From Mycobacterium Smegmatis in Complex with N-Acetyl-D- Glucosamine-6-Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:27.0
occ:1.00
 OE1 B:GLU122 2.1 32.7 1.0
NE2 B:HIS58 2.1 30.8 1.0
NE2 B:HIS56 2.1 24.1 1.0
CL B:CL404 2.2 30.5 1.0
CD B:GLU122 3.0 30.7 1.0
CE1 B:HIS58 3.0 28.1 1.0
CE1 B:HIS56 3.1 24.4 1.0
CD2 B:HIS58 3.1 26.7 1.0
CD2 B:HIS56 3.1 26.0 1.0
OE2 B:GLU122 3.3 33.1 1.0
CD B:CD403 3.6 27.8 1.0
NE2 B:HIS134 3.7 29.8 1.0
CE1 B:HIS134 4.0 36.6 1.0
ND1 B:HIS58 4.2 29.1 1.0
ND1 B:HIS56 4.2 25.3 1.0
CG B:HIS58 4.2 28.9 1.0
CG B:HIS56 4.3 26.5 1.0
CB B:ALA267 4.3 26.0 1.0
CG B:GLU122 4.3 27.1 1.0
CB B:GLU122 4.6 32.3 1.0
CD2 B:HIS209 4.7 29.1 1.0
CA B:ALA267 4.8 30.4 1.0
NE2 B:HIS209 4.8 26.4 1.0
CE B:MET269 4.9 29.6 0.4
CD2 B:HIS134 4.9 41.6 1.0
CB B:SER91 4.9 29.8 1.0

Reference:

M.S.Ahangar, C.M.Furze, C.S.Guy, C.Cooper, K.S.Maskew, B.Graham, A.D.Cameron, E.Fullam. Structural and Functional Determination of Homologs of Themycobacterium Tuberculosis N-Acetylglucosamine-6-Phosphate Deacetylase (Naga). J. Biol. Chem. V. 293 9770 2018.
ISSN: ESSN 1083-351X
PubMed: 29728457
DOI: 10.1074/JBC.RA118.002597
Page generated: Thu Aug 21 14:28:25 2025

Last articles

Zn in 9UUO
Zn in 9UUS
Zn in 9W4R
Zn in 9VKW
Zn in 9W4S
Zn in 9VH1
Zn in 9RMX
Zn in 9RMU
Zn in 9QWN
Zn in 9U9Y
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy