Atomistry » Zinc » PDB 6div-6dxt » 6dve
Atomistry »
  Zinc »
    PDB 6div-6dxt »
      6dve »

Zinc in PDB 6dve: Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer

Enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer

All present enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer:
2.7.7.6;

Protein crystallography data

The structure of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer, PDB code: 6dve was solved by W.Lin, K.Das, Y.Feng, R.H.Ebright, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.68 / 3.81
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 142.762, 160.613, 240.181, 90.00, 90.00, 90.00
R / Rfree (%) 20 / 24.8

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer (pdb code 6dve). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer, PDB code: 6dve:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 6dve

Go back to Zinc Binding Sites List in 6dve
Zinc binding site 1 out of 2 in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2001

b:57.6
occ:1.00
 SG D:CYS968 2.4 82.0 1.0
SG D:CYS978 2.4 86.8 1.0
SG D:CYS975 2.4 63.9 1.0
SG D:CYS891 2.4 0.4 1.0
CB D:CYS968 2.6 67.0 1.0
CB D:CYS978 2.8 84.4 1.0
CA D:CYS968 3.1 57.8 1.0
CB D:CYS891 3.5 75.2 1.0
CB D:CYS975 3.8 76.8 1.0
C D:CYS968 4.0 58.0 1.0
CA D:CYS978 4.1 80.4 1.0
N D:CYS968 4.2 65.0 1.0
N D:CYS975 4.2 62.8 1.0
N D:CYS978 4.2 66.6 1.0
N D:ALA969 4.3 79.4 1.0
N D:CYS891 4.4 87.1 1.0
CA D:CYS975 4.5 68.2 1.0
NH2 D:ARG963 4.6 79.8 1.0
CA D:CYS891 4.6 78.6 1.0
O D:CYS975 4.7 78.9 1.0
OG1 D:THR893 4.7 77.8 1.0
OG1 D:THR970 4.7 76.6 1.0
O D:SER964 4.7 72.9 1.0
C D:CYS975 4.9 63.5 1.0
O D:CYS968 4.9 65.3 1.0

Zinc binding site 2 out of 2 in 6dve

Go back to Zinc Binding Sites List in 6dve
Zinc binding site 2 out of 2 in the Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mycobacterium Tuberculosis Transcription Initiation Complex(Ecf Selenomethionine-Labelled Sigma Factor L) with 6 Nt Spacer within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2002

b:82.3
occ:1.00
 SG D:CYS62 2.4 33.4 1.0
SG D:CYS78 2.4 90.7 1.0
SG D:CYS75 2.5 1.0 1.0
SG D:CYS60 2.6 0.9 1.0
CB D:CYS60 3.0 84.0 1.0
CB D:CYS75 3.2 31.9 1.0
N D:CYS62 3.7 55.1 1.0
CB D:CYS62 3.7 86.2 1.0
CB D:CYS78 4.0 77.0 1.0
N D:TYR61 4.0 68.2 1.0
CA D:CYS62 4.2 90.5 1.0
CD1 D:TYR65 4.2 86.5 1.0
CA D:CYS60 4.3 69.0 1.0
N D:GLY63 4.4 86.6 1.0
N D:LYS64 4.4 83.9 1.0
C D:CYS60 4.5 70.1 1.0
N D:CYS78 4.5 94.8 1.0
CB D:LYS64 4.6 83.8 1.0
C D:CYS62 4.6 90.3 1.0
C D:TYR61 4.7 59.5 1.0
CA D:CYS75 4.7 45.3 1.0
N D:TYR65 4.8 45.6 1.0
CA D:CYS78 4.8 87.6 1.0
CE1 D:TYR65 4.8 81.8 1.0
CA D:TYR61 4.9 62.6 1.0

Reference:

W.Lin, S.Mandal, D.Degen, M.S.Cho, Y.Feng, K.Das, R.H.Ebright. Structural Basis of Ecf-Sigma-Factor-Dependent Transcription Initiation. Nat Commun V. 10 710 2019.
ISSN: ESSN 2041-1723
PubMed: 30755604
DOI: 10.1038/S41467-019-08443-3
Page generated: Mon Oct 28 19:50:22 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy